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GRID2 anticorps

GRID2 Reactivité: Humain, Souris, Rat WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN317812
  • Antigène Voir toutes GRID2 Anticorps
    GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))
    Reactivité
    • 16
    • 13
    • 13
    • 2
    Humain, Souris, Rat
    Hôte
    • 14
    • 2
    Lapin
    Clonalité
    • 15
    • 1
    Polyclonal
    Conjugué
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRID2 est non-conjugé
    Application
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificité
    This antibody detects endogenous levels of GluR delta-2 protein.(region surrounding Gly860)
    Purification
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product GRID2 Anticorps primaire
  • Indications d'application
    ELISA: 1/20000 - 1/40000. Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))
    Autre désignation
    Glutamate Receptor delta-2 (GRID2 Produits)
    Synonymes
    anticorps GluD2, anticorps glurd2, anticorps si:rp71-1l7.1, anticorps GRID2, anticorps B230104L07Rik, anticorps GluRdelta2, anticorps Lc, anticorps Lc, anticorps MMS10-AC, anticorps Ms10ac, anticorps cpr, anticorps ho, anticorps nmf408, anticorps tpr, anticorps glutamate receptor, ionotropic, delta 2, anticorps glutamate receptor ionotropic, delta-2, anticorps glutamate ionotropic receptor delta type subunit 2, anticorps grid2, anticorps LOC704787, anticorps GRID2, anticorps Grid2, anticorps LOC536367
    Sujet
    Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits, designated GluR-1 to -7, as well as GluR-δ2. The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: ε1, 2, 3, 4 and one ζ subunit. The ζ subunit is expressed throughout the brainstem whereas the four ε subunits display limited distribution. In mice, mutations in the gene encoding GluR-δ2 (GRID2) cause the Lurcher phenotype. The gene encoding human GluR-δ2 maps to chromosome 4q22.Synonyms: GLURD2, GRID2, GluR delta-2
    Poids moléculaire
    approx. 113 kDa
    ID gène
    2895
    NCBI Accession
    NP_001501
    UniProt
    O43424
    Pathways
    Synaptic Membrane
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