SERPINA5 anticorps

N° du produit ABIN317849

Détail du produit anti-SERPINA5 anticorps

Antigène: SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPINA5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: PAI-3 antibody detects endogenous levels of PAI-3 protein.(region surrounding Leu291)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SERPINA5

Antigène: SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))

Autre désignation: SERPINA5 (SERPINA5 Produits)

Synonymes: anticorps 4933415L04, anticorps PAI-3, anticorps Pci, anticorps PAI3, anticorps PCI, anticorps PCI-B, anticorps PLANH3, anticorps PROCI, anticorps serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5, anticorps serpin family A member 5, anticorps serine (or cysteine) peptidase inhibitor, clade A, member 5, anticorps plasma serine protease inhibitor, anticorps SPIA5, anticorps SERPINA5, anticorps Serpina5, anticorps LOC480424

Sujet: PAI-1, PAI-2 and PAI-3 (plasminogen activator inhibitor-1, -2 and -3) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation. PAI-3 inhibits plasminogen activators as well as activated protein C. PAI-3 is secreted in plasma, but is also expressed in liver.Synonyms: Acrosomal serine protease inhibitor, PAI-3, PAI3, PCI, PLANH3, PROCI, Plasma serine protease inhibitor, Plasminogen activator inhibitor 3, Protein C inhibitor, Serpin A5

Poids moléculaire: approx. 42 kDa

ID gène: 5104

NCBI Accession: NP_000615

UniProt: P05154