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BAG1 anticorps (N-Term)

BAG1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN318740
  • Antigène Voir toutes BAG1 Anticorps
    BAG1 (BCL2-Associated Athanogene (BAG1))
    Épitope
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 34
    • 19
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain, Souris
    Hôte
    • 31
    • 8
    Lapin
    Clonalité
    • 30
    • 9
    Polyclonal
    Conjugué
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BAG1 est non-conjugé
    Application
    • 31
    • 14
    • 12
    • 11
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This antibody detects an epitope within the N-terminal (NT) region of Bcl-2 associated athanogene-1 (BAG1).
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse.
    Purification
    Affinity chromatography
    Immunogène
    14 amino acid peptide near the amino terminus of human BAG1.
    Isotype
    IgG
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    Discover our top product BAG1 Anticorps primaire
  • Indications d'application
    Western Blot: 1 - 2g/mL, detects a band of approximately 35 kDa in PC3 cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline containing 0.02 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    BAG1 (BCL2-Associated Athanogene (BAG1))
    Autre désignation
    BAG1 (BAG1 Produits)
    Synonymes
    anticorps BAG-1, anticorps HAP, anticorps RAP46, anticorps Rap46, anticorps Bag-1, anticorps ATBAG1, anticorps BCL-2-associated athanogene 1, anticorps MSG15.15, anticorps MSG15_15, anticorps im:7148830, anticorps si:dkey-216e9.4, anticorps BCL2 associated athanogene 1, anticorps putative bcl2-associated athanogene, anticorps BCL2-associated athanogene 1, anticorps Bcl2 associated athanogene 1, anticorps BAG family molecular chaperone regulator 1, anticorps BCL-2-associated athanogene 1, anticorps BAG1, anticorps Smp_005900, anticorps Bag1, anticorps bag-1, anticorps LOC781741, anticorps bag1
    Sujet
    BAG1 is a co-chaperone protein which binds to and regulates the 70kD heat shock proteins (Hsp70/Hsc70). BAG1 has also been shown to interact with the kinase Raf1, a number of steroid and tyrosine kinase receptors, and the Bcl-2 family of proteins. It is thought to function as a molecular switch between cell growth and differentiation, and cell survival. The BAG1 gene encodes three different isoforms, a predominantly cytosolic form of 36kD (BAG1S), a 46kD cytosolic and nuclear form (BAG1M), and a predominantly nuclear form 50kD (BAG1L). BAG1 displays potent neuroprotective activity in vivo against stroke, and could be used for reducing brain injury during cerebral ischemia and neurodegenerative diseases. BAG1 may also promote chemoresistance, growth factor independence, and anchorage independent cell growth in tumour cells.Synonyms: BAG family molecular chaperone regulator 1, BAG-1, Bcl-2-associated athanogene 1, Glucocorticoid receptor-associated protein RAP46, HAP, RAP46
    ID gène
    573
    NCBI Accession
    NP_001165886
    UniProt
    Q99933
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