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HRK anticorps (Middle Region)

HRK Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN318751
  • Antigène Voir toutes HRK Anticorps
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    Épitope
    • 15
    • 13
    • 7
    • 2
    • 2
    • 1
    Middle Region
    Reactivité
    • 29
    • 23
    • 18
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 44
    Lapin
    Clonalité
    • 44
    Polyclonal
    Conjugué
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HRK est non-conjugé
    Application
    • 18
    • 14
    • 13
    • 13
    • 9
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This antibody detects Harakiri (HRK), also known as DP5.
    Purification
    Purified
    Immunogène
    15 amino acid peptide from near the centre of human HRK (NP_003797).
    Isotype
    IgG
    Top Product
    Discover our top product HRK Anticorps primaire
  • Indications d'application
    Western Blot: 2 - 5g/mL, detects a band of approximately 13 kDa in mouse pancreas tissuelysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Précaution d'utilisation
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    Autre désignation
    Harakiri / HRK (HRK Produits)
    Synonymes
    anticorps DP5, anticorps HARAKIRI, anticorps AI838259, anticorps Bid3, anticorps harakiri, anticorps Dp5, anticorps harakiri, BCL2 interacting protein, anticorps harakiri, BCL2 interacting protein (contains only BH3 domain), anticorps HRK, anticorps Hrk
    Sujet
    HRK is a BH3 only protein of the Bcl-2 family, which promotes Bax dependent apoptosis. HRK regulates apoptosis through its interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL, and in conjunction to the mitochondrial pore forming protein p32. HRK is thought to have a specific role in initiating neuronal and haematopoietic cell apoptosis, in particular to growth factor deprivation. Aberrant methylation of HRK is frequently detected in primary colorectal cancers. Despite its predicted molecular weight, HRK often migrates at 12-15kD.Synonyms: Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3, BID3, Neuronal death protein DP5
    ID gène
    8739
    NCBI Accession
    NP_003797
    UniProt
    O00198
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