Amylin/DAP anticorps

N° du produit ABIN334637

Détail du produit anti-Amylin/DAP anticorps

Antigène: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reactivité: Humain

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp Amylin/DAP est non-conjugé

Application: Western Blotting (WB), ELISA

Attributs du produit: Expected / apparent Molecular Weight of the Antigene: 4 kDa

Purification: affinity purified

Immunogène: synthetic peptide based on human IAPP sequence: K-C-N-T-A-T-C-A-T-Q-R-L-A-N-F-L-V-H-S-S-N-N-F-G-A-I-L-S-S-T-N-V-G-S-N-T-Y

Isotype: IgY

Information d'application

Indications d'application: Recommended Dilution: 1 : 1000 (WB), 1 : 1000 (ELISA).

Commentaires:

antibody is recognizing trimer, dimer and monomer human IAPP

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 8.0 + 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Make aliquots to avoid repreated freeze-thaw cycles and working with a stock.

Stock: 4 °C

Détails sur Amylin/DAP

Antigène: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Autre désignation: IAPP (IAPP Produits)

Synonymes: anticorps DAP, anticorps IAP, anticorps LOC100230121, anticorps Amylin, anticorps islet amyloid polypeptide, anticorps IAPP, anticorps Iapp

Sujet: Amylin, or Islet Amyloid Polypeptide (IAPP) P10997, is a 37-residue peptide hormone secreted by pancreatic beta-cells at the same time as insulin (in a roughly 1:100 amylin:insulin ratio). Islet, or insulinoma, almyloid polypeptide (IAPP, or amylin) is commonly found in pancreatic islets of patients suffering diabetes mellitus type 2, or harboring an insulinoma. While the association of amylin with the development of type 2 diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Recent results suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzherimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the deleopment of type 2 diabetes.

Poids moléculaire: 4 kDa

Pathways: Hormone Activity, Feeding Behaviour