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ITPR1 anticorps (AA 1892-1911)

ITPR1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Singe IHC, WB, IHC (p), IP, ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN337359
  • Antigène Voir toutes ITPR1 Anticorps
    ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
    Épitope
    • 12
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1892-1911
    Reactivité
    • 49
    • 30
    • 28
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Singe
    Hôte
    • 46
    • 2
    Lapin
    Clonalité
    • 46
    • 3
    Polyclonal
    Conjugué
    • 31
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp ITPR1 est non-conjugé
    Application
    • 21
    • 16
    • 14
    • 10
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Marque
    IHC-plus™
    Specificité
    Recognizes human IP3R-I. Detects a band of ~240kD by Western Blot. Species cross-reactivity: mouse, rat and canine.
    Homologie
    Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine (100%) Hamster, Elephant, Panda, Horse (95%) Opossum (85%).
    Purification
    Affinity purified
    Immunogène
    Synthetic peptide corresponding to aa 1892-1911 (N1892KKKDDEVDRDAPSRKKAKE1911) of the cytoplasmic C-terminal domain of human IP3R-I (inositol 1,4,5-triphosphate receptor (type-I)). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine (100%), Hamster, Elephant, Panda, Horse (95%), Opossum (85%).

    Type of Immunogen: Synthetic peptide
    Isotype
    IgG
    Top Product
    Discover our top product ITPR1 Anticorps primaire
  • Indications d'application
    Approved: ICC, IHC, IHC-Fr (1:125), IHC-P (5 μg/mL), IP, WB (1:500)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.
    Commentaires

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, 1 mg/mL BSA, 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    4°C or -20°C, Avoid freeze-thaw cycles.
  • Antigène
    ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
    Autre désignation
    ITPR1 / IP3 Receptor Type 1 (ITPR1 Produits)
    Synonymes
    anticorps D6Pas2, anticorps ENSMUSG00000072853, anticorps Gm10429, anticorps IP3R1, anticorps InsP3R, anticorps Ip3r, anticorps Itpr-1, anticorps P400, anticorps Pcp-1, anticorps Pcp1, anticorps opt, anticorps I145TR, anticorps InsP3R1, anticorps INSP3R1, anticorps IP3R, anticorps SCA15, anticorps SCA16, anticorps SCA29, anticorps inositol 1,4,5-trisphosphate receptor type 1, anticorps inositol 1,4,5-trisphosphate receptor 1, anticorps inositol 1,4,5-trisphosphate receptor, type 1, anticorps ITPR1, anticorps Itpr1
    Sujet
    Name/Gene ID: ITPR1
    Subfamily: Inositol 1,4,5-triphosphate receptor
    Family: Ion Channel

    Synonyms: ITPR1, InsP3R-I, IP3R1, InsP3R, InsP3R type I, INSP3R1, IP3R, Opisthotonus, Pcp1, IP3 receptor, IP3 receptor isoform 1, SCA15, Spinocerebellar ataxia 15, Spinocerebellar ataxia 16, I145TR, IP3R 1, KIAA1754, SCA16, Type 1 InsP3 receptor
    ID gène
    3708
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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