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DRAM anticorps (N-Term)

DRAM1 Reactivité: Souris WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN350297
  • Antigène Voir toutes DRAM (DRAM1) Anticorps
    DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
    Épitope
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 18
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Souris
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 14
    • 2
    • 1
    • 1
    Cet anticorp DRAM est non-conjugé
    Application
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Specific for DRAM.
     Réactivité croisée
    Souris, Rat
    Réactivité croisée (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogène
    A synthetic peptide from the n-terminal of mouse DRAM conjugated to an immunogenic carrier protein has been used as the antigen. The peptide is homologous in rat and shares 86% identity with human's.
    Isotype
    IgG
    Top Product
    Discover our top product DRAM1 Anticorps primaire
  • Indications d'application
    IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))
    Autre désignation
    DRAM (DRAM1 Produits)
    Synonymes
    anticorps DRAM1, anticorps DRAM, anticorps 1200002N14Rik, anticorps Dram, anticorps dram, anticorps DNA damage regulated autophagy modulator 1, anticorps DNA-damage regulated autophagy modulator 1, anticorps DNA damage regulated autophagy modulator 1 L homeolog, anticorps DRAM1, anticorps Dram1, anticorps dram1.L
    Sujet
    This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. FUNCTION: Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. SUBCELLULAR LOCATION: Lysosome membrane, Multi-pass membrane protein.,Mammalian Autophagy,Damage-regulated autophagy modulator
    UniProt
    Q9DC58
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