PKD2L1 anticorps (Polycystic Kidney Disease 2-Like 1) (1st Cytoplasmic Loop)

N° du produit ABIN350747

Détail du produit anti-PKD2L1 anticorps

Antigène:

PKD2L1

Épitope: 1st Cytoplasmic Loop

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD2L1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Specificité: Specific for PKD2L1.

Purification: Whole serum

Immunogène: A synthetic peptide from the 1t cytoplasmic loop of mouse PKD2L1 conjugated to blue carrier protein was used as the antigen.

Information d'application

Indications d'application: A dilution of 1 : 300 to 1 : 2000 is recommended.
The optimal dilution should be determined by the end user.
Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PKD2L1 (ABIN350747)

Ohishi, Nishida, Miyamoto, Imai, Nakanishi, Kobayashi, Hayashi, Nagasawa: "Bortezomib alters sour taste sensitivity in mice." dans: Toxicology reports, Vol. 4, pp. 172-180, 2017 (PubMed).

Détails sur PKD2L1

Antigène:

PKD2L1

Autre désignation: PKD2L1 (PKD2L1 Antibody Extrait)

Sujet: This gene encodes a member of the polycystin protein family. The encoded protein contains multipletransmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined
Function: May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling.
Subcellular location: Membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in adult heart, skeletal muscle, brain, spleen, testis, retina and liver. According to Ref.1 expressed at high levels in fetal tissues, including kidney and liver, and down-regulated in adult tissues. It has been found to be expressed in fetal brain, but not expressed in fetal lung, liver or kidney. Isoform 4 appears to be expressed only in transformed lymphoblasts. Also known as: PK2L1, PKD2L1, PKD2L, PKDL, Polycystin-L.