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PKD2L1 anticorps (Polycystic Kidney Disease 2-Like 1) (4th Cytoplasmic Loop) Primary Antibody

PKD2L1 Reactivité: Humain IHC, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN350748
$454.67
Plus shipping costs $45.00
100 μL
local_shipping Destination: Etats-Unis
Envoi sous 7 à 8 jours ouvrables
  • Antigène
    PKD2L1
    Épitope
    4th Cytoplasmic Loop
    • 11
    • 9
    • 8
    • 2
    • 1
    • 1
    • 1
    Reactivité
    Humain
    • 31
    • 3
    • 1
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Conjugué
    Cet anticorp PKD2L1 est non-conjugé
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (IHC), Western Blotting (WB)
    • 26
    • 21
    • 4
    • 1
    • 1
    Specificité
    Specific for PKD2L1.
    Purification
    Whole serum
    Immunogène
    A synthetic peptide from the 4th cytoplasmic loop of human PKD2L1 conjugated to an immunogenic carrier protein was used as the antigen.
  • Indications d'application
    A dilution of 1 : 300 to 1 : 2000 is recommended.
    The optimal dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    PKD2L1
    Autre désignation
    PKD2L1 (PKD2L1 Antibody Extrait)
    Synonymes
    PKD2L1, si:packtrz.2, si:xx-packtrz.2, B830002B15, BC046386, PCL, PKD2L, Pkdl, TRPP3, PKDL, polycystin 2 like 1, transient receptor potential cation channel, polycystic kidney disease 2-like 1, PKD2L1, pkd2l1, Pkd2l1
    Sujet
    This gene encodes a member of the polycystin protein family. The encoded protein contains multipletransmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined
    Function: May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling.
    Subcellular location: Membrane, Multi-pass membrane protein.
    Tissue specificity: Expressed in adult heart, skeletal muscle, brain, spleen, testis, retina and liver. According to Ref.1 expressed at high levels in fetal tissues, including kidney and liver, and down-regulated in adult tissues. It has been found to be expressed in fetal brain, but not expressed in fetal lung, liver or kidney. Isoform 4 appears to be expressed only in transformed lymphoblasts. Also known as: PK2L1, PKD2L1, PKD2L, PKDL, Polycystin-L.
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