PTP4A3 anticorps

N° du produit ABIN356421

Détail du produit anti-PTP4A3 anticorps

Antigène: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTP4A3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody is specific to PRL3.

Attributs du produit: Synonyms: PRL-3, PRL-R, Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3,Protein-tyrosine phosphatase of regenerating liver 3

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This monoclonal antibody is generated from mice immunized with a recombinant protein.

Clone: 111AT714

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PTP4A3

Antigène: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Autre désignation: PRL3 / PTP4A3 (PTP4A3 Produits)

Synonymes: anticorps PRL-3, anticorps PRL-R, anticorps PRL3, anticorps wu:fc54b05, anticorps wu:fv52d11, anticorps zgc:77109, anticorps prl-3, anticorps prl3, anticorps ptpcaax3, anticorps PTP4A3, anticorps AV088979, anticorps Prl-3, anticorps pPtp4a3, anticorps protein tyrosine phosphatase type IVA, member 3, anticorps protein tyrosine phosphatase type IVA, member 3 L homeolog, anticorps protein tyrosine phosphatase 4a3, anticorps PTP4A3, anticorps ptp4a3, anticorps ptp4a3.L, anticorps Ptp4a3

Sujet: PRL3 (PTP4A3) belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.Synonyms: PRL-3, PRL-R, Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3, Protein-tyrosine phosphatase of regenerating liver 3

ID gène: 100131062

UniProt: O75365