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LIN28B anticorps (N-Term)

LIN28B Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357011
  • Antigène Voir toutes LIN28B Anticorps
    LIN28B (Lin-28 Homolog B (LIN28B))
    Épitope
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 55
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 1
    • 1
    Lapin
    Clonalité
    • 53
    • 3
    Polyclonal
    Conjugué
    • 35
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LIN28B est non-conjugé
    Application
    • 41
    • 28
    • 25
    • 23
    • 22
    • 7
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects LIN28B at N-term.
    Purification
    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human LIN28B.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LIN28B Anticorps primaire
  • Indications d'application
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    LIN28B (Lin-28 Homolog B (LIN28B))
    Autre désignation
    LIN28B (LIN28B Produits)
    Synonymes
    anticorps csdd2, anticorps LIN-28, anticorps CSDD2, anticorps 2810403D23Rik, anticorps D030047M17Rik, anticorps Lin-28.2, anticorps lin-28 homolog B, anticorps lin-28 homolog B S homeolog, anticorps lin-28 homolog B (C. elegans), anticorps LIN28B, anticorps lin28b, anticorps lin28b.S, anticorps Lin28b
    Sujet
    Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma. The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans. Similar with lin-28 proteins, LIN28B conserves a cold shock domain and a pair of CCHC zinc finger domains. Phylogenetic analysis suggests that they might arise as a result of duplication from an ancestral gene. Overexpression of LIN28B was noted in most HCC cell lines and clinical samples. A short LIN28B isoform was also identified in non-tumor liver tissue and fetal liver. Although predominantly localized in the cytoplasm, LIN28B protein shows cell cycle-dependent nuclear translocation in Huh7 cells. Induced expression of exogenous LIN28B in a tet-off cell line promoted cancer cell proliferation.Synonyms: CSDD2, LIN28B, Lin-28 homolog B
    Poids moléculaire
    26953 Da
    ID gène
    389421, 9606
    UniProt
    Q6ZN17
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