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LIN28B anticorps (Center)

LIN28B Reactivité: Humain WB, FACS, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357013
  • Antigène Voir toutes LIN28B Anticorps
    LIN28B (Lin-28 Homolog B (LIN28B))
    Épitope
    • 11
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 55
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 1
    • 1
    Lapin
    Clonalité
    • 53
    • 3
    Polyclonal
    Conjugué
    • 35
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp LIN28B est non-conjugé
    Application
    • 41
    • 27
    • 25
    • 23
    • 21
    • 6
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects LIN28B at center.
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    KLH conjugated synthetic peptide selected from the Center region of human LIN28B
    Isotype
    Ig Fraction
    Top Product
    Discover our top product LIN28B Anticorps primaire
  • Indications d'application
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    LIN28B (Lin-28 Homolog B (LIN28B))
    Autre désignation
    LIN28B (LIN28B Produits)
    Synonymes
    anticorps csdd2, anticorps LIN-28, anticorps CSDD2, anticorps 2810403D23Rik, anticorps D030047M17Rik, anticorps Lin-28.2, anticorps lin-28 homolog B, anticorps lin-28 homolog B S homeolog, anticorps lin-28 homolog B (C. elegans), anticorps LIN28B, anticorps lin28b, anticorps lin28b.S, anticorps Lin28b
    Sujet
    Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma. The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans. Similar with lin-28 proteins, LIN28B conserves a cold shock domain and a pair of CCHC zinc finger domains. Phylogenetic analysis suggests that they might arise as a result of duplication from an ancestral gene. Overexpression of LIN28B was noted in most HCC cell lines and clinical samples. A short LIN28B isoform was also identified in non-tumor liver tissue and fetal liver. Although predominantly localized in the cytoplasm, LIN28B protein shows cell cycle-dependent nuclear translocation in Huh7 cells. Induced expression of exogenous LIN28B in a tet-off cell line promoted cancer cell proliferation.Synonyms: CSDD2, LIN28B, Lin-28 homolog B
    Poids moléculaire
    26953 Da
    ID gène
    389421, 9606
    UniProt
    Q6ZN17
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