STAM anticorps (C-Term)
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- Antigène Voir toutes STAM Anticorps
- STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
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Épitope
- C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STAM est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody is specific to STAM (C-term).
- Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human STAM.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product STAM Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
- Autre désignation
- STAM1 (STAM Produits)
- Synonymes
- anticorps STAM-1, anticorps STAM1, anticorps wu:fv75b10, anticorps zgc:55725, anticorps RGD1564499, anticorps signal transducing adaptor molecule, anticorps signal transducing adapter molecule 1, anticorps Signal transducing adapter molecule 1, anticorps signal transducing adaptor molecule (SH3 domain and ITAM motif) 1, anticorps STAM, anticorps CpipJ_CPIJ003516, anticorps Tsp_03939, anticorps stam-1, anticorps Stam, anticorps stam
- Sujet
- Stimulation of cells with cytokines initiates a signal transduction cascade involving cytokine receptors, Janus kinases (JAKs) and signal transducers and activators of transcription (STATs). STAM for 'signal-transducing adaptor molecule, induced after stimulation of cells with cytokine IL2, is a component of signal transduction downstream of JAK3.1 Human STAM cDNA cloned from a T-cell cDNA library encodes a 540-amino acid protein precipitated by anti-phosphotyrosine. Northern blot analysis indicates that STAM is expressed as a 2.9-kb message in a wide variety of tissue and cell types. The STAM sequence contains a Src-homology 3 (SH3) domain and an immunoreceptor tyrosine-based activation motif (ITAM). It has been suggested that STAM acts as an adaptor molecule in signal transduction pathways from cytokine receptors.Synonyms: HSE1 homolog, STAM, STAM-1, Signal transducing adapter molecule 1
- Poids moléculaire
- 59179 Da
- ID gène
- 8027, 9606
- UniProt
- Q92783
- Pathways
- EGFR Signaling Pathway, EGFR Downregulation
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