ABCB7
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
HRP
Indications d'application
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Antigène
ABCB7
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 7 (ABCB7))
anticorps CG7955, anticorps Dmel\\CG7955, anticorps dABCB7, anticorps GB11034, anticorps ABCB7, anticorps fc20c02, anticorps wu:fc20c02, anticorps ABC7, anticorps ASAT, anticorps Atm1p, anticorps EST140535, anticorps AA517758, anticorps AU019072, anticorps Abc7, anticorps ATP binding cassette subfamily B member 7, anticorps ATP-binding cassette sub-family B member 7, mitochondrial, anticorps ATP-binding cassette, sub-family B (MDR/TAP), member 7, anticorps ATP-binding cassette sub-family B member 7, mitochondrial-like, anticorps ABCB7, anticorps LOC412749, anticorps abcb7, anticorps LOC100367778, anticorps LOC100467128, anticorps Abcb7
Sujet
The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.Synonyms: ABC7, ATP-binding cassette sub-family B member 7 mitochondrial