NME3 anticorps (AA 59-88)

N° du produit ABIN359315

Détail du produit anti-NME3 anticorps

Antigène: NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))

Épitope: AA 59-88

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NME3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes NME3.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59~88 from the center region of Human NME3.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur NME3

Antigène: NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))

Autre désignation: NME3 (NME3 Produits)

Synonymes: anticorps DR-nm23, anticorps NDPK-C, anticorps NDPKC, anticorps NM23-H3, anticorps NM23H3, anticorps c371H6.2, anticorps 1810009F08Rik, anticorps AI413736, anticorps Ndk3, anticorps Nm23-DR, anticorps Nm23-M3, anticorps NME/NM23 nucleoside diphosphate kinase 3, anticorps NME3, anticorps Nme3

Sujet: NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.Synonyms: DR-nm23, NDK 3, NDK-3, NDK3, NDP kinase 3, NDPKC, Nucleoside diphosphate kinase 3, Nucleoside diphosphate kinase C, nm23-H3

ID gène: 4832, 9606

UniProt: Q13232

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process