GATA1 anticorps (pSer310)

N° du produit ABIN361955

Détail du produit anti-GATA1 anticorps

Antigène: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Épitope: pSer310

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificité: The antibody detects endogenous level of GATA1 only when phosphorylated at serine 310.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Immunogène: Peptide sequence around phosphorylation site of pSer310 (K-A-S (p) -G-K) derived from Human GATA1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotype: IgG

Information d'application

Indications d'application: Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur GATA1

Antigène: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Autre désignation: GATA1 (GATA1 Produits)

Synonymes: anticorps ERYF1, anticorps GATA-1, anticorps GF-1, anticorps GF1, anticorps NF-E1, anticorps NFE1, anticorps XLANP, anticorps XLTDA, anticorps XLTT, anticorps Gata-1, anticorps Gf-1, anticorps eryf1, anticorps Eryf1, anticorps GATA1, anticorps gata-1, anticorps Gata1, anticorps si:dkeyp-77f7.5, anticorps gata1, anticorps gata1a-A, anticorps xGATA-1, anticorps xgata1, anticorps XGATA-1B, anticorps gata1b-A, anticorps gta1, anticorps zg1, anticorps NF-E1a, anticorps GATA binding protein 1, anticorps GATA binding protein 1 (globin transcription factor 1), anticorps amidase, anticorps aspartyl/glutamyl-tRNA amidotransferase subunit A, anticorps putative amidase, anticorps GatA1, anticorps glutamyl-tRNA amidotransferase subunit A, anticorps hematopietic transcription factor GATA-1, anticorps GATA binding protein 1b, anticorps GATA binding protein 1 L homeolog, anticorps GATA binding protein 1 S homeolog, anticorps GATA binding protein 1a, anticorps erythroid transcription factor, anticorps GATA1, anticorps Gata1, anticorps gatA1, anticorps gata-1, anticorps gata1b, anticorps gata1.L, anticorps gata1.S, anticorps gata1a, anticorps LOC108348091

Sujet: GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

Poids moléculaire: 43 kDa

NCBI Accession: NP_002040

UniProt: P15976

Pathways: Cellular Response to Molecule of Bacterial Origin