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NOD2 anticorps (N-Term)

NOD2 Reactivité: Humain WB, IF, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN372921
  • Antigène Voir toutes NOD2 Anticorps
    NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
    Épitope
    • 16
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    • 39
    • 5
    • 4
    Humain
    Hôte
    • 38
    • 3
    • 1
    Lapin
    Clonalité
    • 40
    • 2
    Polyclonal
    Conjugué
    • 21
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NOD2 est non-conjugé
    Application
    • 36
    • 17
    • 14
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody recognizes NOD2 Protein (CARD15).
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography.
    Immunogène
    Synthetic peptide - KLH conjugated corresponding to 16 amino acids at the amino terminus of Human NOD2.
    Isotype
    IgG
    Top Product
    Discover our top product NOD2 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 2-4 μg/mL. Immunocytochemistry: 5 μg/mL. Immunohistochemistry on Paraffin Sections: 3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
    Autre désignation
    CARD15 / NOD2 (NOD2 Produits)
    Synonymes
    anticorps ACUG, anticorps BLAU, anticorps CARD15, anticorps CD, anticorps CLR16.3, anticorps IBD1, anticorps NLRC2, anticorps NOD2B, anticorps PSORAS1, anticorps Card15, anticorps F830032C23Rik, anticorps Nlrc2, anticorps caspase recruitment domain 15 protein, anticorps nucleotide binding oligomerization domain containing 2, anticorps nucleotide-binding oligomerization domain containing 2, anticorps TTHERM_01951320, anticorps NOD2, anticorps Nod2
    Sujet
    CARD15 (Nod2) is a member of the Nod1/Apaf-1 family of intracellular proteins that contain an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and a C-terminal regulatory domain. CARD15 induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. It also confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Unlike Nod1, this homologue is primary expressed in monocytes. Defects in CARD15 are associated with Blau Syndrome (BS) and Crohn's Disease (CD), and are a cause of susceptibility to ulcerative colitis.Synonyms: Caspase recruitment domain-containing protein 15, IBD1, Inflammatory bowel disease protein 1, Nucleotide-binding oligomerization domain-containing protein 2
    ID gène
    64127
    NCBI Accession
    NP_071445
    UniProt
    Q9HC29
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome
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