EGLN3 anticorps (Internal Region)
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- Antigène Voir toutes EGLN3 Anticorps
- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EGLN3 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes EGLN3.
- Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human. - Purification
- Affinity chromatography
- Immunogène
- Peptide with sequence C-RLGKYYVKERSK, from the internal region of the protein sequence
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- Discover our top product EGLN3 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/8000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0,5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
- Autre désignation
- EGLN3 / PHD3 (EGLN3 Produits)
- Synonymes
- anticorps zgc:77019, anticorps wu:fj78a08, anticorps EGLN3, anticorps phd3, anticorps PHD-3, anticorps PHD3, anticorps SM-20, anticorps 2610021G09Rik, anticorps AI505553, anticorps AI648162, anticorps Hif-p4h-3, anticorps Phd3, anticorps HIFP4H3, anticorps HIFPH3, anticorps egl-9 family hypoxia-inducible factor 3, anticorps egl-9 family hypoxia inducible factor 3, anticorps egl-9 family hypoxia-inducible factor 3 L homeolog, anticorps egln3, anticorps EGLN3, anticorps egln3.L, anticorps Egln3
- Sujet
- PHD3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins, hydroxylates HIF-1 alpha at Pro-564, and also hydroxylates HIF-2 alpha. It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex. It may play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. It promotes cell death through a caspase-dependent mechanism.Synonyms: Egl nine homolog 3, HIF PH3, HIF-PH3, HIF-prolyl hydroxylase 3, HPH-1, HPH-3, Hypoxia-inducible factor prolyl hydroxylase 3, Prolyl hydroxylase domain-containing protein 3
- ID gène
- 112399
- NCBI Accession
- NP_071356
- UniProt
- Q9H6Z9
- Pathways
- Positive Regulation of Endopeptidase Activity
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