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PRDM2 anticorps (AA 1-347)

PRDM2 Reactivité: Humain, Souris WB, ChIP Hôte: Souris Monoclonal 33AT1045 unconjugated
N° du produit ABIN387783
  • Antigène Voir toutes PRDM2 Anticorps
    PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
    Épitope
    • 15
    • 15
    • 9
    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-347
    Reactivité
    • 63
    • 13
    • 12
    Humain, Souris
    Hôte
    • 54
    • 12
    Souris
    Clonalité
    • 55
    • 11
    Monoclonal
    Conjugué
    • 19
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PRDM2 est non-conjugé
    Application
    • 40
    • 30
    • 26
    • 26
    • 21
    • 16
    • 8
    • 6
    • 3
    • 2
    • 2
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Purification
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogène
    Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This antibody is specific for RIZ1, it does not recognize the isoform beta (RIZ2).
    Clone
    33AT1045
    Isotype
    IgG1
  • Indications d'application
    CHIP: 1:100. CHIP: 1:100. CHIP: 1:100. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Lakshmikuttyamma, Takahashi, Pastural, Torlakovic, Amin, Garcia-Manero, Voralia, Czader, DeCoteau, Geyer: "RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression." dans: Journal of hematology & oncology, Vol. 2, pp. 28, (2009) (PubMed).

    Carling, Kim, Yang, Gu, Zhang, Huang: "A histone methyltransferase is required for maximal response to female sex hormones." dans: Molecular and cellular biology, Vol. 24, Issue 16, pp. 7032-42, (2004) (PubMed).

  • Antigène
    PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))
    Autre désignation
    PRDM2 (RIZ1) (PRDM2 Produits)
    Synonymes
    anticorps MGC114763, anticorps prdm2, anticorps riz, anticorps kmt8, anticorps riz1, anticorps riz2, anticorps mtb-zf, anticorps humhoxy1, anticorps PRDM2, anticorps HUMHOXY1, anticorps KMT8, anticorps MTB-ZF, anticorps RIZ, anticorps RIZ1, anticorps RIZ2, anticorps 4833427P12Rik, anticorps E330024L24Rik, anticorps Gm1033, anticorps Gm19732, anticorps Riz, anticorps Riz1, anticorps Znfpr1c1, anticorps PR domain containing 2, with ZNF domain S homeolog, anticorps PR domain containing 2, with ZNF domain b, anticorps PR domain containing 2, with ZNF domain, anticorps PR domain zinc finger protein 2, anticorps PR/SET domain 2, anticorps prdm2.S, anticorps prdm2b, anticorps prdm2, anticorps LOC100350859, anticorps PRDM2, anticorps Prdm2
    Sujet
    This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    188915
    ID gène
    7799
    NCBI Accession
    NP_001007258, NP_001129082, NP_036363, NP_056950
    UniProt
    Q13029
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