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SUV39H2 anticorps (N-Term)

SUV39H2 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB02737 unconjugated
N° du produit ABIN388081
  • Antigène Voir toutes SUV39H2 Anticorps
    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
    Épitope
    • 15
    • 13
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 93-122, N-Term
    Reactivité
    • 77
    • 28
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 75
    • 2
    • 1
    Lapin
    Clonalité
    • 69
    • 9
    Polyclonal
    Conjugué
    • 34
    • 8
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SUV39H2 est non-conjugé
    Application
    • 62
    • 48
    • 31
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This SUV39H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the N-terminal region of human SUV39H2.
    Clone
    RB02737
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SUV39H2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Hung, Lin, Yeh, Chang: "Histone-modifying genes as biomarkers in hepatocellular carcinoma." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 5, pp. 2496-507, (2015) (PubMed).

    Chen, Yeh, Yang, Chang, Lee, Hung: "High expressions of histone methylation- and phosphorylation-related proteins are associated with prognosis of oral squamous cell carcinoma in male population of Taiwan." dans: Medical oncology (Northwood, London, England), Vol. 30, Issue 2, pp. 513, (2013) (PubMed).

    Benlhabib, Mendelson: "Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia." dans: Molecular and cellular biology, Vol. 31, Issue 10, pp. 1949-58, (2011) (PubMed).

  • Antigène
    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
    Autre désignation
    SUV39H2 (SUV39H2 Produits)
    Synonymes
    anticorps KMT1B, anticorps 4930507K23Rik, anticorps AA536750, anticorps D030054H19Rik, anticorps D2Ertd544e, anticorps SUV39H2, anticorps kmt1b, anticorps suppressor of variegation 3-9 homolog 2, anticorps suppressor of variegation 3-9 homolog 2 (Drosophila), anticorps suppressor of variegation 3-9 homolog 2 L homeolog, anticorps SUV39H2, anticorps Suv39h2, anticorps suv39h2, anticorps suv39h2.L
    Sujet
    The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59 % identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.
    Poids moléculaire
    46682
    ID gène
    79723
    NCBI Accession
    NP_001180353, NP_001180354, NP_001180355, NP_001180356, NP_078946
    UniProt
    Q9H5I1
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