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HRK anticorps (AA 15-50)

HRK Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB04688 unconjugated
N° du produit ABIN388104
  • Antigène Voir toutes HRK Anticorps
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    Épitope
    • 15
    • 13
    • 7
    • 2
    • 2
    AA 15-50
    Reactivité
    • 28
    • 22
    • 18
    • 2
    • 2
    • 2
    • 1
    Humain, Souris
    Hôte
    • 43
    Lapin
    Clonalité
    • 43
    Polyclonal
    Conjugué
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HRK est non-conjugé
    Application
    • 18
    • 14
    • 13
    • 13
    • 8
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This Hrk BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-50 amino acids from human Hrk BH3 Domain.
    Clone
    RB04688
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HRK Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))
    Autre désignation
    Hrk (HRK Produits)
    Synonymes
    anticorps DP5, anticorps HARAKIRI, anticorps AI838259, anticorps Bid3, anticorps harakiri, anticorps Dp5, anticorps harakiri, BCL2 interacting protein, anticorps harakiri, BCL2 interacting protein (contains only BH3 domain), anticorps HRK, anticorps Hrk
    Sujet
    Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL.
    Poids moléculaire
    9884
    ID gène
    8739
    NCBI Accession
    NP_003797
    UniProt
    O00198
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