ABCG2 anticorps (Center)

N° du produit ABIN388306

Détail du produit anti-ABCG2 anticorps

Antigène: ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))

Épitope: AA 305-335, Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCG2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This ABCG2 (BCRP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313~342 amino acids from the center region of human ABCG2.

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This ABCG2 (BCRP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 AA from the Central region of human ABCG2 (BCRP).

Clone: RB13782

Isotype: Ig Fraction

Information d'application

Indications d'application: WB = 1:1000, IF = 1:10-50, FACS = 1:10-50, IHC (p) = 1:50-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ABCG2

Antigène: ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))

Autre désignation: ABCG2 (BCRP) (ABCG2 Produits)

Synonymes: anticorps bcrp, anticorps ABCG2, anticorps ABC15, anticorps ABCP, anticorps BCRP, anticorps BCRP1, anticorps BMDP, anticorps CD338, anticorps CDw338, anticorps EST157481, anticorps GOUT1, anticorps MRX, anticorps MXR, anticorps MXR1, anticorps UAQTL1, anticorps AI428558, anticorps Bcrp1, anticorps ABCG3, anticorps ATP binding cassette subfamily G member 2, anticorps ATP binding cassette subfamily G member 2 (Junior blood group), anticorps ATP binding cassette subfamily G member 2 (Junior blood group) L homeolog, anticorps ATP-binding cassette, sub-family G (WHITE), member 2, anticorps ATP-binding cassette sub-family G member 2, anticorps ABCG2, anticorps abcg2, anticorps abcg2.L, anticorps Abcg2, anticorps LOC100008640

Sujet: ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.
Synonyms: ATP-binding cassette sub-family G member 2, Placenta-specific ATP-binding cassette transporter, Breast cancer resistance protein, Mitoxantrone resistance-associated protein, CD338 antigen, CDw338, ABCP, BCRP, BCRP1, MXR

Poids moléculaire: 72314 DA

ID gène: 9429

UniProt: Q9UNQ0

Pathways: Transition Metal Ion Homeostasis