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NCAPH2 anticorps (N-Term)

NCAPH2 Reactivité: Humain WB Hôte: Lapin Polyclonal RB9657 unconjugated
N° du produit ABIN388692
  • Antigène Voir toutes NCAPH2 Anticorps
    NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))
    Épitope
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 198-227, N-Term
    Reactivité
    • 16
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 15
    • 1
    Lapin
    Clonalité
    • 15
    • 1
    Polyclonal
    Conjugué
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NCAPH2 est non-conjugé
    Application
    • 14
    • 9
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogène
    This NCAPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the N-terminal region of human NCAPH2.
    Clone
    RB9657
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Lai, Wong, Lee, Li: "Caspase-3-mediated degradation of condensin Cap-H regulates mitotic cell death." dans: Cell death and differentiation, Vol. 18, Issue 6, pp. 996-1004, (2011) (PubMed).

    Lisková, Susor, Pivonková, Sasková, Karabínová, Kubelka: "Detection of condensin I and II in maturing pig oocytes." dans: Reproduction, fertility, and development, Vol. 22, Issue 4, pp. 644-52, (2010) (PubMed).

  • Antigène
    NCAPH2 (Non-SMC Condensin II Complex, Subunit H2 (NCAPH2))
    Autre désignation
    NCAPH2 (NCAPH2 Produits)
    Synonymes
    anticorps MGC81656, anticorps CAPH2, anticorps si:dkey-202b22.2, anticorps non-SMC condensin II complex subunit H2, anticorps non-SMC condensin II complex subunit H2 L homeolog, anticorps non-SMC condensin II complex, subunit H2, anticorps NCAPH2, anticorps ncaph2.L, anticorps ncaph2, anticorps Ncaph2
    Sujet
    Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.
    Poids moléculaire
    68227
    ID gène
    29781
    NCBI Accession
    NP_001171940, NP_055366, NP_689512
    UniProt
    Q6IBW4
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