MMP 9 anticorps (C-Term)

N° du produit ABIN390154

Détail du produit anti-MMP 9 anticorps

Antigène: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Épitope: AA 644-673, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP 9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MMP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 644-673 amino acids from the C-terminal region of human MMP9.

Clone: RB02019-RB02020

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:50~100. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-MMP 9 (ABIN390154)

Dou, Cao, Wang, Zhang, Huang, Lian, Xie, Wang: "EFEMP1 inhibits migration of hepatocellular carcinoma by regulating MMP2 and MMP9 via ERK1/2 activity." dans: Oncology reports, Vol. 35, Issue 6, pp. 3489-95, (2017) (PubMed).

Du, Wang, Tan, Li, Huang, Huang, Yang, Zhang, Wang, Huang, Huang: "Nkx2-5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E-Deficient Mice." dans: Journal of the American Heart Association, Vol. 5, Issue 12, (2017) (PubMed).

Huang, Chiu, Chou, Su, Chen, Chai, Huang, Huang, Yuan, Lee: "Association of MMP-2 and MMP-9 expression with recurrences in primary spontaneous pneumothorax." dans: The Kaohsiung journal of medical sciences, Vol. 33, Issue 1, pp. 17-23, (2017) (PubMed).

Dai, Duan, Duan, Zhou, He, Tu, Shen: "Down-regulation of TCF21 by hypermethylation induces cell proliferation, migration and invasion in colorectal cancer." dans: Biochemical and biophysical research communications, (2015) (PubMed).

Alfonso-Loeches, Ureña-Peralta, Morillo-Bargues, Gómez-Pinedo, Guerri: "Ethanol-Induced TLR4/NLRP3 Neuroinflammatory Response in Microglial Cells Promotes Leukocyte Infiltration Across the BBB." dans: Neurochemical research, (2015) (PubMed).

Shi, Shang, Pan, Wang, Jiang, Hao, Zhang, Cai, Xu, Zhan, Wang: "Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 23, pp. 6153-62, (2014) (PubMed).

Shi, Yang, Shen, Yang, Xu, Qiu, Sun, Zhang, Wang, Zhu, Qin, Tang, Fan, Zhou: "High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery." dans: Cancer, Vol. 119, Issue 5, pp. 993-1003, (2013) (PubMed).

Wu, Wang, Guo, Ye, Wang, Yuan, Yao, Shang: "A lipoxin A4 analog ameliorates blood-brain barrier dysfunction and reduces MMP-9 expression in a rat model of focal cerebral ischemia-reperfusion injury." dans: Journal of molecular neuroscience : MN, Vol. 46, Issue 3, pp. 483-91, (2012) (PubMed).

Chen, Wang, Hu, Chang, Liao, Dai, Juo: "OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 5, pp. 1718-28, (2011) (PubMed).

Détails sur MMP 9

Antigène: MMP 9 (MMP9) (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9))

Autre désignation: MMP9 (MMP9 Produits)

Synonymes: anticorps CLG4B, anticorps GELB, anticorps MANDP2, anticorps MMP-9, anticorps AW743869, anticorps B/MMP9, anticorps Clg4b, anticorps pro-MMP-9, anticorps mmp-9, anticorps fgMMP-9, anticorps mmp9, anticorps ZFMMP-9, anticorps wu:fb02g06, anticorps wu:fb07b05, anticorps wu:fi98c09, anticorps wu:fj05a08, anticorps zgc:64165, anticorps clg4b, anticorps gelb, anticorps mandp2, anticorps matrix metallopeptidase 9, anticorps collagenase, anticorps matrix metalloproteinase 9, anticorps matrix metallopeptidase 9 S homeolog, anticorps MMP9, anticorps RB3913, anticorps BPSS0666, anticorps Sbal_3732, anticorps Bcer98_0486, anticorps Shew185_0630, anticorps Shal_3056, anticorps Sbal195_0657, anticorps Lbys_3550, anticorps Palpr_2084, anticorps Mmp9, anticorps mmp9, anticorps mmp9.S

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Poids moléculaire: 78458

ID gène: 4318

NCBI Accession: NP_004985

UniProt: P14780

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events