This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This NUR77(NR4A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from human NUR77(NR4A1).
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Geradts, Groth, Wu, Jin: "Validation of an oligo-gene signature for the prognostic stratification of ductal carcinoma in situ (DCIS)." dans: Breast cancer research and treatment, Vol. 157, Issue 3, pp. 447-59, (2017) (PubMed).
Antigène
NR4A1
(Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
anticorps GFRP1, anticorps HMR, anticorps N10, anticorps NAK-1, anticorps NGFIB, anticorps NP10, anticorps NUR77, anticorps TR3, anticorps NGFI-B, anticorps Gfrp, anticorps Hbr-1, anticorps Hbr1, anticorps Hmr, anticorps TIS1, anticorps nur77, anticorps Ngfi-b, anticorps Nur77, anticorps nuclear receptor subfamily 4 group A member 1, anticorps nuclear receptor subfamily 4, group A, member 1, anticorps NR4A1, anticorps Nr4a1
Sujet
NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. This protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis.