PRKAG3 anticorps (AA 148-178)

N° du produit ABIN391060

Détail du produit anti-PRKAG3 anticorps

Antigène: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Épitope: AA 148-178

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAG3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PRKAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-178 amino acids from the Central region of human PRKAG3.

Clone: RB3191

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PRKAG3 (ABIN391060)

Okoshi, Ohta, Ishikawa, Sato, Kizaki: "Expression of 5'-AMP-activated protein kinase with starvation in murine thymocytes." dans: The Bulletin of Tokyo Dental College, Vol. 52, Issue 1, pp. 21-9, (2011) (PubMed).

Fukuyama, Ohta, Okoshi, Suehara, Kizaki, Nakagawa: "Hypoxia induces expression and activation of AMPK in rat dental pulp cells." dans: Journal of dental research, Vol. 86, Issue 9, pp. 903-7, (2007) (PubMed).

Détails sur PRKAG3

Antigène: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Autre désignation: PRKAG3 (PRKAG3 Produits)

Synonymes: anticorps Ampkg3, anticorps prkag3-a, anticorps PRKAG3, anticorps AMPKG3, anticorps AMPKg3L, anticorps AMPKg3S, anticorps Amkg3, anticorps protein kinase AMP-activated non-catalytic subunit gamma 3, anticorps protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog, anticorps protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b, anticorps protein kinase, AMP-activated, gamma 3 non-catatlytic subunit, anticorps Prkag3, anticorps PRKAG3, anticorps prkag3.S, anticorps prkag3-b

Sujet: PRKAG3 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Poids moléculaire: 54258

ID gène: 53632

NCBI Accession: NP_059127

UniProt: Q9UGI9

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, L'effet Warburg