CKMT1 anticorps (N-Term)

N° du produit ABIN391091

Détail du produit anti-CKMT1 anticorps

Antigène: CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))

Épitope: AA 55-84, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT1 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, Pig, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CKMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the N-terminal region of human CKMT1.

Clone: RB5397-5398

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur CKMT1

Antigène: CKMT1 (Creatine Kinase, Mitochondrial 1, Ubiquitous (CKMT1))

Abstract: CKMT1 Produits

Synonymes: anticorps fb37h03, anticorps fb69a12, anticorps wu:fb37h03, anticorps wu:fb69a12, anticorps Mt-CK, anticorps ScCKmit, anticorps UbCKmit, anticorps mi-CK, anticorps Ckmt1, anticorps creatine kinase, mitochondrial 1, anticorps creatine kinase, mitochondrial 1, ubiquitous, anticorps ckmt1, anticorps Ckmt1

Sujet: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase.

Poids moléculaire: 47037

ID gène: 548596

NCBI Accession: NP_001015001, NP_066270

UniProt: P12532