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CYP3A4 anticorps (AA 228-255)
CYP3A4
Reactivité: Humain
WB, FACS, IHC (p)
Hôte: Lapin
Polyclonal
RB15792
unconjugated
Détail du produit anti-CYP3A4 anticorps
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Antigène
Voir toutes CYP3A4 Anticorps
CYP3A4
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
Épitope
Tous les épitopes à travers CYP3A4 Anticorps.
AA 228-255
Reactivité
Toutes les réactivités sur CYP3A4 Anticorps
Humain
Hôte
Toutes les hôtes sur CYP3A4 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CYP3A4 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CYP3A4 Anticorps
Cet anticorp CYP3A4 est non-conjugé
Application
Tous les applications à travers CYP3A4 Anticorps.
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This CYP3A4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-255 amino acids from the Central region of human CYP3A4.
Clone
RB15792
Isotype
Ig Fraction
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Alternatives
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anti-Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) (AA 18-120) antibody
CYP3A4
Reactivité: Humain, Souris, Rat
WB, FACS, IF (p), IHC (p), ICC, IF (cc), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Détails sur CYP3A4
(cache)
Antigène
CYP3A4
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
Autre désignation
CYP3A4 (CYP3A4 Produits )
Synonymes
anticorps CP33, anticorps CP34, anticorps CYP3A, anticorps CYP3A3, anticorps CYPIIIA3, anticorps CYPIIIA4, anticorps HLP, anticorps NF-25, anticorps P450C3, anticorps P450PCN1, anticorps MGC108372, anticorps CYP3A80, anticorps CYP3A4, anticorps CYP3A21, anticorps CYPIIIA21, anticorps CYP3A12, anticorps cytochrome P450 family 3 subfamily A member 4, anticorps cytochrome P450 family 3 subfamily A member 43, anticorps cytochrome P450 3A4, anticorps cytochrome P450, subfamily IIIA, polypeptide 4, anticorps cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, anticorps cytochrome P450, family 3, subfamily A, polypeptide 4, anticorps CYP3A4, anticorps CYP3A43, anticorps PTRG_01782, anticorps PTRG_06060, anticorps cyp3a4
Sujet
CYP3A4, is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens.
Poids moléculaire
57343
ID gène
1576
NCBI Accession
NP_001189784 , NP_059488
UniProt
P08684
Pathways
Steroid Hormone Biosynthesis
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