CYP2R1 anticorps (AA 152-180)

N° du produit ABIN392380

Détail du produit anti-CYP2R1 anticorps

Antigène: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Épitope: AA 152-180

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2R1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This CYP2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human CYP2R1.

Clone: RB15785

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-CYP2R1 (ABIN392380)

Ochiai, Hirose, Kawamura, Komachi, Yamamoto, Kitaoka, Hatogai, Kusunoki, Kon, Ikarashi, Sugiyama: "Role of the Drug-Metabolizing Enzyme CYP during Mouse Liver Development." dans: Biological & pharmaceutical bulletin, Vol. 39, Issue 12, pp. 2015-2021, (2017) (PubMed).

Détails sur CYP2R1

Antigène: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Autre désignation: CYP2R1 (CYP2R1 Produits)

Synonymes: anticorps cytochrome P450 family 2 subfamily R member 1, anticorps cytochrome P450, family 2, subfamily R, polypeptide 1, anticorps cytochrome P450, family 2, subfamily r, polypeptide 1, anticorps CYP2R1, anticorps cyp2r1, anticorps Cyp2r1

Sujet: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.

Poids moléculaire: 57359

ID gène: 120227

NCBI Accession: NP_078790

UniProt: Q6VVX0

Pathways: Metabolism of Steroid Hormones and Vitamin D