This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This CYP2C8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-105 amino acids from the N-terminal region of human CYP2C8.
anticorps CPC8, anticorps CYPIIC8, anticorps MP-12/MP-20, anticorps CYP2C74, anticorps cpc8, anticorps cyp2c8, anticorps cypiic8, anticorps mp-12/mp-20, anticorps cytochrome P450 family 2 subfamily C member 8, anticorps Cytochrome P450 2C8, anticorps cytochrome P450, family 2, subfamily C, polypeptide 8, anticorps cytochrome P450 family 2 subfamily C member 8 S homeolog, anticorps CYP2C8, anticorps CTN_0597, anticorps cyp2c8.1.S, anticorps cyp2c8.1
Sujet
CYP2C8 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol.