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NR3C2 anticorps

NR3C2 Reactivité: Humain, Rat, Lapin, Poulet WB, IHC, IHC (p) Hôte: Souris Monoclonal H10E4C9F unconjugated
N° du produit ABIN396956
  • Antigène Voir toutes NR3C2 Anticorps
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Reactivité
    • 57
    • 45
    • 30
    • 17
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Humain, Rat, Lapin, Poulet
    Hôte
    • 71
    • 4
    Souris
    Clonalité
    • 70
    • 5
    Monoclonal
    Conjugué
    • 27
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Cet anticorp NR3C2 est non-conjugé
    Application
    • 72
    • 39
    • 39
    • 20
    • 14
    • 11
    • 10
    • 8
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Marque
    IHC-plus™
    Specificité
    Recognizes human MR (mineralocorticoid receptor). Detects a band of ~116kD by Western Blot. Species cross-reactivity: Rat, rabbit and chicken.
    Purification
    Protein G purified
    Immunogène
    Aldosterone.

    Type of Immunogen: Hapten
    Clone
    H10E4C9F
    Isotype
    IgG1
    Top Product
    Discover our top product NR3C2 Anticorps primaire
  • Indications d'application
    Approved: IHC, IHC-P (1:50), WB (1:250)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working dilution for LS-B3162 was determined to be 1:50. Function: Blocks the binding of aldosterone to the MR.
    Commentaires

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.2, 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Li, Tian, Wang, Hu, Qin, Xu, Liu, Hao, Tian: "LINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2." dans: Cancer biology & therapy, Vol. 21, Issue 7, pp. 615-622, (2020) (PubMed).

  • Antigène
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Autre désignation
    Mineralocorticoid Receptor (NR3C2 Produits)
    Synonymes
    anticorps mr, anticorps si:ch211-189l17.1, anticorps LOC100302443, anticorps NR3C2, anticorps LOC443144, anticorps MLR, anticorps MR, anticorps MCR, anticorps NR3C2VIT, anticorps Mlr, anticorps mlr, anticorps nuclear receptor subfamily 3, group C, member 2, anticorps nuclear receptor subfamily 3 group C member 2, anticorps mineralocorticoid receptor, anticorps nuclear receptor subfamily 3 group C member 2 L homeolog, anticorps nr3c2, anticorps NR3C2, anticorps LOC443144, anticorps Nr3c2, anticorps nr3c2.L
    Sujet
    Name/Gene ID: NR3C2
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: NR3C2, MCR, Mineralocorticoid receptor, NR3C2VIT, Aldosterone receptor, Mineralocorticoid receptor 1, MLR, MR
    ID gène
    4306
    UniProt
    P08235
    Pathways
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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