DIO1 anticorps (N-Term)

N° du produit ABIN452912

Détail du produit anti-DIO1 anticorps

Antigène: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Épitope: AA 36-66, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DIO1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects DIO1 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 36~66 amino acids from the N-terminal region of Human DIO1

Information d'application

Indications d'application: Western blot: 1: 100 - 1: 500. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DIO1

Antigène: DIO1 (Deiodinase, Iodothyronine, Type I (DIO1))

Autre désignation: DIO1 (DIO1 Produits)

Synonymes: anticorps 5DI, anticorps TXDI1, anticorps ITDI1, anticorps D1, anticorps DIOI, anticorps Deio1, anticorps cb685, anticorps zgc:92323, anticorps iodothyronine deiodinase 1, anticorps type I iodothyronine deiodinase-like, anticorps deiodinase, iodothyronine, type I, anticorps deiodinase, iodothyronine type 1 L homeolog, anticorps DIO1, anticorps LOC100231867, anticorps Dio1, anticorps dio1.L, anticorps dio1

Sujet: DIO1 is a thiol-requiring propylthiouracil-sensitive oxidoreductase. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It also degrades both hormones by inner ring deiodination (IRD).Synonyms: DIOI, ITDI1, TXDI1, Type I iodothyronine deiodinase, Type-I 5'-deiodinase

Poids moléculaire: 28924 Da

ID gène: 1733

NCBI Accession: NP_000783

UniProt: P49895

Pathways: Hormone Activity