Endothelin-1 Receptor anticorps (AA 132-162)

N° du produit ABIN452933

Détail du produit anti-Endothelin-1 Receptor anticorps

Antigène: Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))

Épitope: AA 132-162

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endothelin-1 Receptor est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Human Endothelin A receptor at Center. Other species not tested.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide selected between aa 132-162 amino acids from the Center region of Human EDNRA

Information d'application

Indications d'application: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Endothelin-1 Receptor

Antigène: Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))

Autre désignation: Endothelin A Receptor (EDNRA Produits)

Synonymes: anticorps ET-A, anticorps ETA, anticorps ETA-R, anticorps ETAR, anticorps ETRA, anticorps hET-AR, anticorps ET-AR, anticorps Endor, anticorps Eta, anticorps RGD1559432, anticorps ETa, anticorps Gpcr10, anticorps ednr-a, anticorps ednra, anticorps wu:fb75g12, anticorps ednraa, anticorps eta, anticorps etar, anticorps etra, anticorps zgc:85942, anticorps endothelin receptor type A, anticorps endothelin receptor type Aa, anticorps endothelin receptor type A L homeolog, anticorps endothelin receptor type Ab, anticorps EDNRA, anticorps Ednra, anticorps ednraa, anticorps ednra.L, anticorps ednra, anticorps ednrab

Sujet: EDNRA is a receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Function: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 Cellular Location: Cell membrane, Multi-pass membrane protein. Tissue Location: Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.Synonyms: EDNRA, ET-A, ETA, ETA-R, ETRA, Endothelin-1 receptor, endothelin receptor type A, hET-AR

Poids moléculaire: 48722 Da

ID gène: 1909

NCBI Accession: NP_001948

UniProt: P25101

Pathways: cAMP Metabolic Process