PTGIS anticorps (C-Term)

N° du produit ABIN453611

Détail du produit anti-PTGIS anticorps

Antigène: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGIS est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to PTGIS.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogène: KLH conjugated synthetic peptide selected from the C-terminal region of human CYP8A1

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PTGIS

Antigène: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Autre désignation: PTGIS (PTGIS Produits)

Sujet: CYP8A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.Synonyms: CYP8, CYP8A1, Prostacyclin Synthase, Prostaglandin I2 Synthase

ID gène: 5740

NCBI Accession: NP_000952

UniProt: Q16647