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alpha 2 Antiplasmin anticorps

SERPINF2 Reactivité: Humain IEP, ID, RID Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN458138
  • Antigène Voir toutes alpha 2 Antiplasmin (SERPINF2) Anticorps
    alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
    Reactivité
    • 55
    • 28
    • 18
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 51
    • 9
    • 4
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 60
    • 8
    Polyclonal
    Conjugué
    • 36
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp alpha 2 Antiplasmin est non-conjugé
    Application
    • 48
    • 25
    • 17
    • 14
    • 13
    • 13
    • 12
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunoelectrophoresis (IEP), Immunodiffusion (ID), Radial Immunodiffusion (RID)
    Specificité
    The antiserum does not cross-react with any other human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. of this antiserum has not been tested in detail.
    Attributs du produit
    Precipitating polyclonal rabbit antiserum to human alpha-2 antiplasmin
    Purification
    Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other human serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.
    Immunogène
    Alpha-2 antiplasmin is a single-chain glycoprotein with a molecular weight of about 65,000.The normal concentration in human plasma is 60 µ g/ml. Platelets contain significant amounts of the protein, which is released along with platelet factor 4, following thrombin stimulation. It can form 1:1 complexes with circulating plasmin. Alpha-2 antiplasmin is the most important inhibitor of plasmin-mediated fibrinolysis, but also capable of inactivating factor XIIa, kallikrein, factor XIa, thrombin and factor Xa. The importance of the alpha-2 antiplasmin as regulator of the fibrinolytic system was detected by the discovery of a congenital deficiency. Alpha-2 antiplasmin has been isolated from pooled plasma. Freund’s complete adjuvant is used in the first step of the immunization procedure.
    Isotype
    IgG
    Top Product
    Discover our top product SERPINF2 Anticorps primaire
  • Indications d'application
    In precipitating techniques as electroimmunodiffusion (Laurell), immunoelectrophoresis and single and double radial immunodiffusion (Mancini, Ouchterlony). Detection of plasmin-antiplasmin complexes in plasma is evident of plasmin formation and fibrinolysis.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal rabbit serum. No foreign proteins added. Antibody titre: Precipitin titre not less than 1:32 when tested against normal human plasma in agar-block immuno-diffus
    Buffer
    Delipidated, heat inactivated, lyophilized, stable whole serum.
    Agent conservateur
    Without preservative
    Stock
    4 °C/-20 °C
    Stockage commentaire
    The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C, prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by add ing 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not ref rozen, and preferably used the same day.
  • Antigène
    alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))
    Autre désignation
    alpha-2 Antiplasmin (SERPINF2 Produits)
    Synonymes
    anticorps A2AP, anticorps AAP, anticorps ALPHA-2-PI, anticorps API, anticorps PLI, anticorps serpin, anticorps AI747498, anticorps Pli, anticorps Serpimf2, anticorps serpinf2, anticorps serpinf2l, anticorps wu:fd57d08, anticorps Dmrs91, anticorps Pedf, anticorps serpin family F member 2, anticorps serpin family F member 1, anticorps serine (or cysteine) peptidase inhibitor, clade F, member 2, anticorps serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a, anticorps SERPINF2, anticorps Serpinf2, anticorps SERPINF1, anticorps serpinf2a, anticorps Serpinf1
    Sujet
    The defined antibody reactivity is restricted to alpha-2 antiplasmin as tested at the level of sensitivity of immuno-precipitation techniques. A single precipitin line is obtained in bidimensional electrophoresis, immunoelectrophoresis and double radial immunodiffusion (Ouchterlony) which shows a reaction of full identity with the purified immunogen
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones
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