C6 anticorps (C-Term)

N° du produit ABIN461987

Détail du produit anti-C6 anticorps

Antigène: C6 (Complement Component 6 (C6))

Épitope: C-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp C6 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.

Purification: Protein A purified

Immunogène: Purified human C6.

Clone: 056B-214-2-4-2

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. Histology Positive Control Tissue: Kidney from post streptococcal glomerulonephritis patients.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Borate buffered saline, 0.09 % sodium azide. Sourced in Ascites.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. Store undiluted.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.

Détails sur C6

Antigène: C6 (Complement Component 6 (C6))

Autre désignation: Complement C6 (C6 Produits)

Synonymes: anticorps zgc:64073, anticorps MGC82168, anticorps c6, anticorps MGC89471, anticorps C6, anticorps AW111623, anticorps complement component 6, anticorps complement C6, anticorps complement component 6, gene 1 L homeolog, anticorps complement component 6, gene 2, anticorps c6, anticorps C6, anticorps c6.1.L, anticorps c6.2

Sujet: Name/Gene ID: C6

Synonyms: C6, Complement component C6, Complement C6, Complement component 6

ID gène: 729

UniProt: P13671