PYGM anticorps (C-Term)

N° du produit ABIN356948

Détail du produit anti-PYGM anticorps

Antigène: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PYGM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PYGM at C-term.

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PYGM.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-PYGM (ABIN356948)

Hathout, Marathi, Rayavarapu, Zhang, Brown, Seol, Gordish-Dressman, Cirak, Bello, Nagaraju, Partridge, Hoffman, Takeda, Mah, Henricson, McDonald: "Discovery of serum protein biomarkers in the mdx mouse model and cross-species comparison to Duchenne muscular dystrophy patients." dans: Human molecular genetics, Vol. 23, Issue 24, pp. 6458-69, (2015) (PubMed).

Détails sur PYGM

Antigène: PYGM (Phosphorylase, Glycogen, Muscle (PYGM))

Autre désignation: Glycogen Phosphorylase Muscle Form (PYGM Produits)

Synonymes: anticorps pygb, anticorps im:7150327, anticorps zgc:110706, anticorps AI115133, anticorps PG, anticorps Muscpho, anticorps zgc:63642, anticorps phosphorylase, glycogen, muscle L homeolog, anticorps glycogen phosphorylase, muscle associated, anticorps phosphorylase, glycogen, muscle A, anticorps glycogen phosphorylase, muscle form, anticorps muscle glycogen phosphorylase, anticorps phosphorylase, glycogen, muscle b, anticorps pygm.L, anticorps PYGM, anticorps pygma, anticorps THA_70, anticorps Pygm, anticorps pygmb

Sujet: PYGM catalyzes and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5), also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.Synonyms: GPMM, Myophosphorylase, PYGM, Phosphorylase A, Phosphorylase B

Poids moléculaire: 97092 Da

ID gène: 5837, 9606

UniProt: P11217

Pathways: Cellular Glucan Metabolic Process