NGFR anticorps (Nerve Growth Factor Receptor) (Extracellular Domain)

Details for Product anti-NGFR Antibody No. ABIN462128
Antigène
Épitope
Extracellular Domain
16
16
13
13
9
9
7
7
6
4
4
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Chat, Humain, Singe, Lapin
335
133
126
55
50
49
45
44
29
10
6
6
4
3
2
2
2
2
1
1
Hôte
Souris
181
175
12
4
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp NGFR est non-conjugé
23
15
11
10
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
192
159
136
120
103
67
48
35
27
17
16
16
16
15
6
6
4
3
3
3
1
Options
Marque IHC-plus™
Immunogène Nerve Growth Factor Receptor from A875 melanoma cells. Cellular Localization: Cell surface and cytoplasmic.

Type of Immunogen: Cells
Clone NGFR5
Isotype IgG1, kappa
Specificité Recognizes a glycoprotein of 75kD, identified as low affinity Nerve Growth Factor Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Epitope: aa1-160 of extracellular domain of NGFR/NTR. Species cross-reactivity: Human, monkey (Cebus apella, Macaca fascicularis, Mulatta and Nemestrina), baboon (Papio anubis and Cynocephalus), feline, rabbit and ferret. Does not cross-react with mouse or rat.
Purification Protein G purified
Antigène
Autre désignation NGFR / CD271 / p75 (NGFR Antibody Extrait)
Sujet Name/Gene ID: NGFR
Family: TNF Receptor

Synonyms: NGFR, CD271, CD271 antigen, gp80-LNGFR, Nerve growth factor receptor, p75 ICD, p75(NTR), p75NTR, TNFR superfamily, member 16, NGF receptor, TNFRSF16
ID gène 4804
UniProt P08138
Pathways Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
Indications d'application Approved: Flo, IF, IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Not recommended for: WB
Commentaires

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 10 mM PBS,  pH 7.4.
Agent conservateur Azide free
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C,-20 °C
Stockage commentaire 4°C or -20°C, Avoid freeze-thaw cycles.
Images (Fournisseur)
Image no. 1 for anti-Nerve Growth Factor Receptor (NGFR) (Extracellular Domain) antibody (ABIN462128) Human Adrenal, Nerve (formalin-fixed, paraffin-embedded) stained with NGFR antibody A...
Image no. 2 for anti-Nerve Growth Factor Receptor (NGFR) (Extracellular Domain) antibody (ABIN462128) Human Small Intestine, Submucosal Plexus (formalin-fixed, paraffin-embedded) stained ...
Image no. 3 for anti-Nerve Growth Factor Receptor (NGFR) (Extracellular Domain) antibody (ABIN462128) Human Prostate (formalin-fixed, paraffin-embedded) stained with NGFR antibody ABIN462...