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ADAM17 anticorps (pThr735)

ADAM17 Reactivité: Humain, Rat, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN482093
  • Antigène Voir toutes ADAM17 Anticorps
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Épitope
    • 16
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-750, pThr735
    Reactivité
    • 115
    • 54
    • 52
    • 4
    • 4
    • 4
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 100
    • 13
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 92
    • 25
    Polyclonal
    Conjugué
    • 54
    • 11
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADAM17 est non-conjugé
    Application
    • 87
    • 53
    • 40
    • 15
    • 14
    • 14
    • 12
    • 11
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    Specificité

    ADAM 17 (Phospho-Thr735) Antibody detects endogenous levels of ADAM 17 only when phosphorylated at Thr735.

    PhosphorylationH:T735 M:T735 R:T735

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Pureté
    > 95 %
    Immunogène
    The antiserum was produced against synthesized peptide derived from human ADAM 17 around the phosphorylation site of Thr735.
    Isotype
    IgG
    Top Product
    Discover our top product ADAM17 Anticorps primaire
  • Indications d'application
    WB: 1:500~1:1000 ELISA: 1:20000
    Commentaires

    Unigene-Number: Hs.404914 (NCBI Gene Symbol: ADAM17)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Stable at -20°C for at least 1 year.
    Date de péremption
    12 months
  • Bilousova, Taylor, Emirzian, Gylys, Frautschy, Cole, Teng: "Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease." dans: Neurobiology of disease, Vol. 74, pp. 32-40, (2015) (PubMed).

  • Antigène
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    Autre désignation
    ADAM 17 (ADAM17 Produits)
    Synonymes
    anticorps ADAM18, anticorps CD156B, anticorps CSVP, anticorps NISBD, anticorps TACE, anticorps CD156b, anticorps Tace, anticorps adam17, anticorps si:dkey-81b15.2, anticorps adam18, anticorps cd156b, anticorps csvp, anticorps tace, anticorps fc20b01, anticorps wu:fc20b01, anticorps zgc:63886, anticorps ADAM metallopeptidase domain 17, anticorps a disintegrin and metallopeptidase domain 17, anticorps ADAM metallopeptidase domain 17b, anticorps ADAM metallopeptidase domain 17 L homeolog, anticorps ADAM metallopeptidase domain 17a, anticorps ADAM17, anticorps Adam17, anticorps adam17b, anticorps adam17.L, anticorps adam17a
    Sujet

    Synonyms: ADA17, ADAM 17, CD156b antigen, CSVP, TACE, TNF-alpha convertase, TNF-alpha-converting enzyme, a disintegrin and metalloproteinase domain 17, snake venom-like protease

    NCBI Gene Symbol: ADAM17

    Poids moléculaire
    93 kDa
    ID gène
    6868
    OMIM
    603639
    UniProt
    P78536
    Pathways
    Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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