ABCE1 anticorps (AA 419-599)

N° du produit ABIN4886410

Détail du produit anti-ABCE1 anticorps

Antigène: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Épitope: AA 419-599

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCE1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family E member 1(ABCE1) detection. Tested with WB in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family E member 1(ABCE1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ATP binding cassette subfamily E member 1
Protein Name: ATP-binding cassette sub-family E member 1

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human ABCE1 recombinant protein (Position: K419-D599). Human ABCE1 shares 100% amino acid (aa) sequence identity with mouse ABCE1.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ABCE1

Antigène: ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

Autre désignation: ABCE1 (ABCE1 Produits)

Synonymes: anticorps ABCE1, anticorps DDBDRAFT_0188931, anticorps DDBDRAFT_0191227, anticorps DDB_0188931, anticorps DDB_0191227, anticorps abce1, anticorps MGC69546, anticorps DKFZp469K1416, anticorps ABC38, anticorps OABP, anticorps RLI, anticorps RNASEL1, anticorps RNASELI, anticorps RNS4I, anticorps C79080, anticorps Oabp, anticorps RNS41, anticorps Rnaseli, anticorps wu:fb34c09, anticorps wu:fe47b01, anticorps wu:fi09g07, anticorps zgc:111906, anticorps zgc:56045, anticorps Rns4i, anticorps ATP binding cassette subfamily E member 1, anticorps 4Fe-4S ferredoxin, iron-sulfur binding domain-containing protein, anticorps ATP-binding cassette sub-family E member 1, anticorps RNAse L inhibitor, anticorps RNase L inhibitor, anticorps ribosome biogenesis/translation initiation ATPase RLI, anticorps ATP-binding cassette, sub-family E (OABP), member 1, anticorps ATP binding cassette subfamily E member 1 S homeolog, anticorps ABCE1, anticorps abcE1, anticorps LOC100184673, anticorps LOC100213121, anticorps abce1, anticorps TP04_0855, anticorps PVX_115370, anticorps TERMP_RS03360, anticorps Abce1, anticorps abce1.S

Sujet: ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis.

Synonyms: ABC 38 | ABC38 | ABCE 1 | ABCE1 | HuHP 68 | HuHP68 | OABP | Ribonuclease 4 inhibitor | Ribonuclease L inhibitor | RLI | RNase L inhibitor | RNASEL1 | RNASELI | RNS 4I | RNS4I | P61221

ID gène: 6059

UniProt: P61221