Catalase anticorps (AA 344-527)

N° du produit ABIN4886504

Détail du produit anti-Catalase anticorps

Antigène: Catalase (CAT)

Épitope: AA 344-527

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Catalase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Catalase(CAT) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Catalase(CAT) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: catalase
Protein Name: Catalase

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Catalase recombinant protein (Position: E344-L527). Human Catalase shares 85.3% and 82.6% amino acid (aa) sequence identity with mouse and rat Catalase, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur Catalase

Antigène: Catalase (CAT)

Autre désignation: CAT (CAT Produits)

Synonymes: anticorps 2210418N07, anticorps Cas-1, anticorps Cas1, anticorps Cs-1, anticorps CS1, anticorps Cat01, anticorps Catl, anticorps fb68a12, anticorps wu:fb68a12, anticorps CAT, anticorps CATA, anticorps CG6871, anticorps CT21282, anticorps CatA, anticorps DMCATHPO, anticorps DROCATHPO, anticorps Dmel\\CG6871, anticorps U00145, anticorps bs36h11.y1, anticorps cat, anticorps GB11648, anticorps catalase, anticorps Cat, anticorps BA0843, anticorps DKFZp469E0232, anticorps catalase, anticorps Catalase, anticorps catalase, gene 2, anticorps CAT, anticorps Cat, anticorps cat, anticorps cat.2, anticorps LOC769804, anticorps BA_0843

Sujet: Catalase is a key antioxidant enzyme in the bodies defensing against oxidative stress. It is also a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.

Synonyms: Cas1 | CAT | Catalase | Cs1 | P04040

ID gène: 847

UniProt: P04040

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism