WNK1 anticorps (Middle Region)

N° du produit ABIN4886765

Détail du produit anti-WNK1 anticorps

Antigène: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Épitope: AA 1154-1195, Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase WNK1(WNK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: DNPEEIATIM VNNDFILAIE RESFVDQVRE IIEKADEMLS ED

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase WNK1(WNK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: WNK lysine deficient protein kinase 1
Protein Name: Serine/threonine-protein kinase WNK1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human WNK1 (1154-1195aa DNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSED), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur WNK1

Antigène: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Autre désignation: WNK1 (WNK1 Produits)

Synonymes: anticorps HSAN2, anticorps HSN2, anticorps KDP, anticorps PRKWNK1, anticorps PSK, anticorps p65, anticorps WNK1, anticorps kdp, anticorps psk, anticorps hsn2, anticorps hsan2, anticorps pha2c, anticorps prkwnk1, anticorps 6430573H23Rik, anticorps EG406236, anticorps Hsn2, anticorps Prkwnk1, anticorps mKIAA0344, anticorps ATWNK1, anticorps T9J14.14, anticorps T9J14_14, anticorps ZIK4, anticorps with no lysine (K) kinase 1, anticorps WNK lysine deficient protein kinase 1, anticorps WNK lysine deficient protein kinase 1 L homeolog, anticorps serine/threonine-protein kinase WNK1, anticorps with no lysine (K) kinase 1, anticorps WNK1, anticorps wnk1.L, anticorps wnk1, anticorps LOC100056745, anticorps Wnk1

Sujet: WNK lysine deficient protein kinase 1, also known as WNK1, is an enzyme that in humans is encoded by the WNK1 gene. The human gene is located on short arm of chromosome 12 (12p13.3). This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.

Synonyms: HSAN2 | HSN2 | KDP | Kinase deficient protein | p65 | PRKWNK1 | PSK | WNK1 | WNK 1 | Q9H4A3

ID gène: 65125

UniProt: Q9H4A3