WWP1 anticorps (Internal Region)

N° du produit ABIN4889365

Détail du produit anti-WWP1 anticorps

Antigène: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Reacts with human WWP1 protein

Purification: Purified (protein A)

Immunogène: Synthetic peptide derived from internal part of human WWP1 protein

Information d'application

Indications d'application:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only :
WB(1:200 - 1:2000)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur WWP1

Antigène: WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))

Autre désignation: NEDD4-Like E3 Ubiquitin-Protein Ligase WWP1 (WWP1 Produits)

Synonymes: anticorps AIP5, anticorps Tiul1, anticorps hSDRP1, anticorps 8030445B08Rik, anticorps SDRP1, anticorps WWP1, anticorps aip5, anticorps tiul1, anticorps hsdrp1, anticorps WW domain containing E3 ubiquitin protein ligase 1, anticorps WWP1, anticorps Wwp1, anticorps wwp1

Sujet: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF

UniProt: Q9H0M0