RHOH anticorps (C-Term)

N° du produit ABIN4889497

Détail du produit anti-RHOH anticorps

Antigène: RHOH (Ras Homolog Family Member H (RHOH))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Reacts with human RhoH protein

Purification: Purified (protein A)

Immunogène: Synthetic peptide derived from C terminal domain of human RhoH

Information d'application

Indications d'application:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- IHC : 1/200 to 1/2 000 - WB : 1/500 to 1/5 000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur RHOH

Antigène: RHOH (Ras Homolog Family Member H (RHOH))

Autre désignation: rho-Related GTP-Binding Protein RhoH (RHOH Produits)

Synonymes: anticorps ARHH, anticorps TTF, anticorps 5830400A04Rik, anticorps AU019774, anticorps Arhh, anticorps ras homolog family member H, anticorps RHOH, anticorps Rhoh

Sujet: Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection.

UniProt: Q15669