IL1R2 anticorps (Interleukin 1 Receptor, Type II) (AA 14-355)

Details for Product anti-IL1R2 Antibody No. ABIN4899247
Antigène
  • CD121b
  • CDw121b
  • IL-1R-2
  • IL-1RT-2
  • IL-1RT2
  • IL1R2c
  • IL1RB
  • Il1r-2
  • IL-1R2
  • interleukin 1 receptor type 2
  • interleukin 1 receptor, type II
  • IL1R2
  • Il1r2
Épitope
AA 14-355
21
18
10
8
7
6
6
4
3
3
2
2
1
1
1
1
1
1
1
1
Reactivité
Souris
149
33
26
2
1
Hôte
Chèvre
103
47
12
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp IL1R2 est non-conjugé
7
5
5
5
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
94
81
21
21
14
13
12
11
8
8
4
4
2
2
1
1
1
1
Options
Immunogène S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL-1 RII, Phe14-Glu355 (predicted), Accession # P27931
Isotype IgG
Specificité Detects mouse IL-1 RII in direct ELISAs and Western blots. In direct ELISAs, approximately 30 % cross-reactivity with recombinant human IL-1 RII is observed and less than 1 % cross-reactivity with recombinant mouse (rm) IL-1 RI, recombinant rat IL-1 Rrp2, rmIL-18 R, and rmIL-18 R beta is observed.
Purification Antigen Affinity-purified
Stérilité 0.2 μm filtered
Plasmids, Primers & others Plasmids, Primers & others IL1R2 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation IL1R2 (IL1R2 Antibody Extrait)
Sujet Alternative Names: beta, CD121b, CD121b antigen, IL-1 R beta, IL1R2, IL1RBCD121 antigen-like family member B, IL-1R-beta, IL1RII, IL-1RII, IL-1RT2, IL-1RT-2, interleukin 1 receptor, type II, Interleukin-1 receptor beta, MGC47725
ID gène 7850
UniProt P27931
Pathways Signalisation NF-kappaB
Indications d'application Western Blot 0.1 μg/mL
Flow Cytometry 0.25 μg/10^6 cells
Immunohistochemistry 5-15 μg/mL
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Agent conservateur Without preservative
Stock 4 °C,-20 °C,-80 °C
Stockage commentaire Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Date de péremption 12 months
Images (Fournisseur)
Flow Cytometry (FACS) image for anti-Interleukin 1 Receptor, Type II (IL1R2) (AA 14-355) antibody (ABIN4899247) Detection of IL-1 RII in EL-4 Mouse Cell Line by Flow Cytometry. EL-4 mouse lymphobla...
Immunohistochemistry (IHC) image for anti-Interleukin 1 Receptor, Type II (IL1R2) (AA 14-355) antibody (ABIN4899247) IL-1 RII in Mouse Spleen. IL-1 RII was detected in perfusion fixed frozen sections of...
Produit citée dans: Martin, Palmer, Rodriguez, Seemayer, Palomo, Talabot-Ayer, Gabay: "Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory Responses." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 7, pp. 2916-2926, 2017 (PubMed). Méthode utilisée: Immunohistochemistry (IHC), Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

OConnor, Sherry, Guest, Freund et al.: "Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with ..." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 11, pp. 6886-93, 2007 (PubMed). Méthode utilisée: ELISA (ELISA), ELISA (ELISA), ELISA (ELISA) (Échantillon (espèces): Mouse (Murine)).

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