E-cadherin anticorps (Cadherin 1, Type 1, E-Cadherin (Epithelial)) (AA 157-709)

Details for Product anti-CDH1 Antibody No. ABIN4899267
Antigène
  • Arc-1
  • CD324
  • CDHE
  • ECAD
  • LCAM
  • UVO
  • E-cadherin
  • cdh1
  • si:dz180o5.2
  • uvo
  • lcam
  • E-Cad
  • XBcad
  • l-cam
  • xcdh1
  • cdhc-A
  • xb-cad
  • XTCAD-1
  • c-cadherin
  • cadherin-1
  • uvomorulin
  • XB-cadherin
  • arc-1
  • cd324
  • cdhe
  • ecad
  • AA960649
  • E-cad
  • Ecad
  • L-CAM
  • Um
  • cadherin 1
  • si:busm1-180o5.2
  • cadherin 1, type 1, E-cadherin (epithelial)
  • cadherin 1, type 1 S homeolog
  • CDH1
  • si:busm1-180o5.2
  • cdh1
  • Cdh1
  • cdh1.S
Épitope
AA 157-709
25
21
16
16
15
15
13
10
9
8
8
6
6
5
5
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris
579
219
193
35
16
16
9
9
9
7
6
6
4
3
3
3
3
3
3
2
1
Hôte
Chèvre
332
281
14
5
2
Clonalité
Polyclonal
Conjugué
Cet anticorp E-cadherin est non-conjugé
38
33
16
15
13
10
10
10
10
10
9
8
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Simple Western (SimWes), Western Blotting (WB)
449
239
188
146
143
115
69
44
38
33
16
14
13
13
10
10
7
6
4
3
1
Options
Immunogène Mouse myeloma cell line NS0-derived recombinant mouse E-Cadherin, Asp157-Val709, Accession # P09803
Isotype IgG
Specificité Detects mouse E-Cadherin in direct ELISAs and Western blots. In direct ELISAs, approximately 75 % cross-reactivity with recombinant rat E-Cadherin is observed and less than 4 % cross-reactivity with rhK-Cadherin, rhCadherin-8, rhCadherin-17, and recombinant mouse P-Cadherin is observed.
Purification Antigen Affinity-purified
Stérilité 0.2 μm filtered
Plasmids, Primers & others Plasmids, Primers & others E-cadherin products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation E-Cadherin (CDH1 Antibody Extrait)
Sujet Alternative Names: Arc-1, CAD1, cadherin 1, E-cadherin (epithelial), cadherin 1, type 1, E-cadherin (epithelial), cadherin-1, calcium-dependent adhesion protein, epithelial, CAM 120/80, CD324, CD324 antigen, CDH1, CDHE, cell-CAM 120/80, Cell-CAM120/80, ECAD, E-cadherin, ECadherin, Epithelial cadherin, LCAM, L-CAM, UVOE-Cadherin, uvomorulin
ID gène 999
UniProt P09803
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
Indications d'application Western Blot 0.5 μg/mL
Simple Western 5 μg/mL
Flow Cytometry 0.25 μg/10^6 cells
Immunohistochemistry 5-15 μg/mL
Immunocytochemistry 5-15 μg/mL
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Agent conservateur Without preservative
Stock 4 °C,-20 °C,-80 °C
Stockage commentaire Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Date de péremption 12 months
Images (Fournisseur)
Image no. 1 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 157-709) antibody (ABIN4899267) E-Cadherin in Mouse Intestinal Organoids. E-Cadherin was detected in immersion fixed ...
Image no. 2 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 157-709) antibody (ABIN4899267) E-Cadherin in Mouse Skin. E-Cadherin was detected in perfusion fixed frozen sections ...
Image no. 3 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 157-709) antibody (ABIN4899267) Detection of Human and Mouse E-Cadherin by Simple WesternTM. Simple Western lane view...
Image no. 4 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 157-709) antibody (ABIN4899267) Detection of Human and Mouse E-Cadherin by Western Blot. Western blot shows lysates o...
Image no. 5 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 157-709) antibody (ABIN4899267) E-Cadherin in Mouse Intestinal Organoids. E-Cadherin was detected in immersion fixed ...
Image no. 6 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 157-709) antibody (ABIN4899267) E-Cadherin in D3 Mouse Embryonic Stem Cell Line. E-Cadherin was detected in immersion...
Image no. 7 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 157-709) antibody (ABIN4899267) E-Cadherin in Mouse Spinal Cord. E-Cadherin was detected in perfusion fixed frozen se...
Produit citée dans: OBrien, Dorsey, Hannan, Hultgren: "Host restriction of Escherichia coli recurrent urinary tract infection occurs in a bacterial strain-specific manner." dans: PLoS pathogens, Vol. 14, Issue 12, pp. e1007457, 2019 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Mouse (Murine)).

Gay, Ridgway, Müller, Hodder, Hedley, Clark, Leach, Jackstadt, Nixon, Huels, Campbell, Bird, Sansom: "Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer." dans: Nature communications, Vol. 10, Issue 1, pp. 723, 2019 (PubMed). Méthode utilisée: Proximity Ligation Assay (PLA) (Échantillon (espèces): Mouse (Murine)).

Nakajima, Ono, Radović, Dizdarević, Tomizawa, Kuroha, Nagamatsu, Hoshi, Matsunaga, Shirakawa, Kurosawa, Miyazaki, Seki, Suzuki, Koseki, Nakamura, Suda, Ohbo: "Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice." dans: Disease models & mechanisms, Vol. 12, Issue 11, 2019 (PubMed). Méthode utilisée: Western Blotting (WB), Western Blotting (WB) (Échantillon (espèces): Mouse (Murine)).

Sakai, Nakayama, Oshima, Kouyama, Niida, Fujii, Ochiai, Nakayama, Mimori, Suzuki, Hong, Ock, Kim, Oshima: "Combined Mutation of Apc, Kras, and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer." dans: Cancer research, Vol. 78, Issue 5, pp. 1334-1346, 2018 (PubMed).

Coutu, Kokkaliaris, Kunz, Schroeder: "Multicolor quantitative confocal imaging cytometry." dans: Nature methods, Vol. 15, Issue 1, pp. 39-46, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Pui, Saga: "NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes." dans: Mechanisms of development, Vol. 149, pp. 27-40, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Nekrasova, Harmon, Broussard, Koetsier, Godsel, Fitz, Gardel, Green: "Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination." dans: Nature communications, Vol. 9, Issue 1, pp. 1053, 2018 (PubMed). Méthode utilisée: Immunocytochemistry (ICC) (Échantillon (espèces): Human).

Wang, Batourina, Schneider, Souza, Swayne, Liu, George, Tate, Dan, Wiessner, Zhuravlev, Canman, Mysorekar, Mendelsohn: "Polyploid Superficial Cells that Maintain the Urothelial Barrier Are Produced via Incomplete Cytokinesis and Endoreplication." dans: Cell reports, Vol. 25, Issue 2, pp. 464-477.e4, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Kim, Okamoto, Huang, Anguiano, Chen, Liu, Cavino, Xin, Na, Hamid, Lee, Zambrowicz, Unger, Murphy, Xu, Yancopoulos, Li, Gromada: "Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice." dans: Cell metabolism, Vol. 25, Issue 6, pp. 1348-1361.e8, 2018 (PubMed).

Scavuzzo, Chmielowiec, Yang, Wamble, Chaboub, Duraine, Tepe, Glasgow, Arenkiel, Brou, Deneen, Borowiak: "Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA." dans: Cell reports, Vol. 25, Issue 13, pp. 3811-3827.e7, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Échantillon (espèces): Mouse (Murine)).

Flemming, Luissint, Nusrat, Parkos: "Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model." dans: JCI insight, Vol. 3, Issue 20, 2018 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Mouse (Murine)).

Treerat, Prince, Cruz-Lagunas, Muñoz-Torrico, Salazar-Lezama, Selman, Fallert-Junecko, Reinhardt, Alcorn, Kaushal, Zuñiga, Rangel-Moreno, Kolls, Khader: "Novel role for IL-22 in protection during chronic Mycobacterium tuberculosis HN878 infection." dans: Mucosal immunology, Vol. 10, Issue 4, pp. 1069-1081, 2017 (PubMed). Méthode utilisée: Immunohistochemistry (IHC), Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Molotkov, Mazot, Brewer, Cinalli, Soriano: "Distinct Requirements for FGFR1 and FGFR2 in Primitive Endoderm Development and Exit from Pluripotency." dans: Developmental cell, Vol. 41, Issue 5, pp. 511-526.e4, 2017 (PubMed). Méthode utilisée: Immunocytochemistry (ICC) (Échantillon (espèces): Mouse (Murine)).

OBrien, Hannan, Yu, Livny, Roberson, Schwartz, Souza, Mendelsohn, Colonna, Lewis, Hultgren: "A mucosal imprint left by prior Escherichia coli bladder infection sensitizes to recurrent disease." dans: Nature microbiology, Vol. 2, pp. 16196, 2016 (PubMed). Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Échantillon (espèces): Mouse (Murine)).

Kato, Katsuki, Kokubo, Masuda, Saga: "Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells." dans: Nature communications, Vol. 7, pp. 11272, 2016 (PubMed). Méthode utilisée: Immunohistochemistry (Paraformaldehyde) (IHC (pfa)), Immunohistochemistry (Paraformaldehyde) (IHC (pfa)), Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) (Échantillon (espèces): Mouse (Murine)).

Ermilov, Kumari, Li, Joiner, Grachtchouk, Allen, Dlugosz, Mistretta: "Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling." dans: PLoS genetics, Vol. 12, Issue 11, pp. e1006442, 2016 (PubMed). Méthode utilisée: Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Échantillon (espèces): Mouse (Murine)).

Huels, Ridgway, Radulescu, Leushacke, Campbell, Biswas, Leedham, Serra, Chetty, Moreaux, Parry, Matthews, Song, Hedley, Kalna, Ceteci, Reed, Meniel, Maguire, Doyle, Söderberg, Barker, Watson, Larue et al.: "E-cadherin can limit the transforming properties of activating β-catenin mutations. ..." dans: The EMBO journal, Vol. 34, Issue 18, pp. 2321-33, 2015 (PubMed). Méthode utilisée: Immunohistochemistry (IHC), Immunohistochemistry (IHC), Immunohistochemistry (IHC) (Échantillon (espèces): Mouse (Murine)).

Ihermann-Hella, Lume, Miinalainen, Pirttiniemi, Gui, Peränen, Charron, Saarma, Costantini, Kuure: "Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion." dans: PLoS genetics, Vol. 10, Issue 3, pp. e1004193, 2014 (PubMed). Méthode utilisée: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Échantillon (espèces): Mouse (Murine)).

Dassah, Almeida, Hahn, Bonaldo, Worgall, Hajjar: "Annexin A2 mediates secretion of collagen VI, pulmonary elasticity and apoptosis of bronchial epithelial cells." dans: Journal of cell science, Vol. 127, Issue Pt 4, pp. 828-44, 2014 (PubMed). Méthode utilisée: Neutralization (Neut), Neutralization (Neut), Neutralization (Neut) (Échantillon (espèces): Mouse (Murine)).

Guan, Bartlett: "MMP20 modulates cadherin expression in ameloblasts as enamel develops." dans: Journal of dental research, Vol. 92, Issue 12, pp. 1123-8, 2014 (PubMed). Méthode utilisée: Western Blotting (WB), Western Blotting (WB) (Échantillon (espèces): Mouse (Murine)).

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