MME anticorps (Membrane Metallo-Endopeptidase) (AA 52-750)

Details for Product anti-MME Antibody No. ABIN4900407
Antigène
  • CALLA
  • CD10
  • NEP
  • SFE
  • 6030454K05Rik
  • C85356
  • Nep
  • neprilysin
  • membrane metalloendopeptidase
  • membrane metallo endopeptidase
  • membrane metallo-endopeptidase
  • MME
  • Mme
Épitope
AA 52-750
25
19
16
12
12
11
10
10
8
8
8
8
6
6
6
5
5
5
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Reactivité
Humain
594
141
124
11
6
4
4
2
2
2
2
1
1
1
1
Hôte
Chèvre
394
219
2
Clonalité
Polyclonal
Conjugué
Cet anticorp MME est non-conjugé
57
46
43
31
9
8
7
7
7
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), ELISA (Capture), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
310
252
177
131
101
87
77
37
31
21
16
13
4
2
2
1
1
Options
Immunogène S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Neprilysin/CD10, Tyr52-Trp750, Accession # P08473
Isotype IgG
Specificité Detects human Neprilysin/CD10 in ELISAs and Western blots. In sandwich ELISAs, approximately 20 % cross-reactivity with recombinant mouse Neprilysin is observed, and less than 0.3 % cross-reactivity with recombinant human Neprilysin-2 is observed.
Purification Immunogen affinity purified
Stérilité 0.2 μm filtered
Plasmids, Primers & others Plasmids, Primers & others MME products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation Neprilysin/CD10 (MME Antibody Extrait)
Sujet Alternative Names: Atriopeptidase, CALLA, CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase), CD10, CD10 antigen, CD10), CD10membrane metallo-endopeptidase variant 1, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24, EC 3.4.24.11, Enkephalinase, EPN, Leu-19, membrane metallo-endopeptidase, membrane metallo-endopeptidase variant 2, MGC126681, MGC126707, MME, NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, neprilysin, Neutral endopeptidase, Neutral Endopeptidase 24.11, NKH1, SFE, Skin fibroblast elastase
ID gène 4311
UniProt P08473
Pathways Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
Indications d'application Western Blot 1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
Immunohistochemistry 5-15 μg/mL
Immunoprecipitation 25 μg/mL
CyTOF-ready
ELISA Capture (Matched Antibody Pair) 0.2-0.8 μg/mL
Restrictions For Research Use only
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Agent conservateur Without preservative
Stock 4 °C,-20 °C,-80 °C
Stockage commentaire Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Date de péremption 12 months
Images (Fournisseur)
Immunohistochemistry (IHC) image for anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody (ABIN4900407) anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
Western Blotting (WB) image for anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody (ABIN4900407) anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody (Image 2)
Produit citée dans: Grimm, Thiel, Lauer, Winkler, Lehmann, Regner, Nelke, Janitschke, Benoist, Streidenberger, Stötzel, Endres, Herr, Beisswenger, Grimm, Bals, Lammert, Hartmann: "Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation." dans: International journal of molecular sciences, Vol. 18, Issue 12, 2018 (PubMed). Méthode utilisée: Activity Assay (AcA) (Échantillon (espèces): Mouse (Murine)).

Lan, Xu, Kiyota, Peng, Zheng, Ikezu: "HIV-1 reduces Abeta-degrading enzymatic activities in primary human mononuclear phagocytes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 12, pp. 6925-32, 2011 (PubMed). Méthode utilisée: ELISA (ELISA), ELISA (ELISA), ELISA (ELISA) (Échantillon (espèces): Human).

Danielyan, Schäfer, Schulz, Ladewig, Lourhmati, Buadze, Schmitt, Verleysdonk, Kabisch, Koeppen, Siegel, Proksch, Kluba, Eckert, Köhle, Schöneberg, Northoff, Schwab, Gleiter: "Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin." dans: Cell death and differentiation, Vol. 16, Issue 12, pp. 1599-614, 2009 (PubMed). Méthode utilisée: Western Blotting (WB), Western Blotting (WB), Western Blotting (WB) (Échantillon (espèces): Human).

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