PDGFRB anticorps (Platelet-Derived Growth Factor Receptor, beta Polypeptide)

Details for Product anti-PDGFRB Antibody No. ABIN4900877
Antigène
  • AI528809
  • CD140b
  • PDGFR-1
  • Pdgfr
  • CD140B
  • IBGC4
  • JTK12
  • PDGFR
  • PDGFR1
  • platelet derived growth factor receptor, beta polypeptide
  • platelet derived growth factor receptor beta
  • Pdgfrb
  • PDGFRB
Reactivité
Humain
511
286
247
9
8
8
8
6
2
2
2
1
1
1
Hôte
Souris
440
96
5
4
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp PDGFRB est non-conjugé
21
15
15
15
15
15
15
15
14
13
11
6
6
6
6
6
4
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
306
146
135
83
79
58
57
23
14
12
7
3
2
2
2
1
Options
Immunogène Human skin fibroblast membrane extracts
Clone PR7212
Isotype IgG1
Specificité Detects human PDGF R beta in Western blots. Specificity has been confirmed in binding studies using several different cell lines (1, 2) and by its ability to immunoprecipitate PDGF receptor beta-subunit complexed with 125I-PDGF-BB (3). It does not recognize the PDGF receptor alpha-subunit. Detects the PDGF receptor beta-subunit of human and primate species (monkey and baboon) but not the rat or mouse receptors. Its ability to bind to receptors from other species has not been tested.
Purification Protein A or G purified from ascites
Stérilité 0.2 μm filtered
Plasmids, Primers & others Plasmids, Primers & others PDGFRB products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation PDGF R beta (PDGFRB Antibody Extrait)
Sujet Alternative Names: beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140b, CD140b antigen, EC 2.7.10, EC 2.7.10.1, JTK12, PDGFR, PDGFR1, PDGFRB, PDGF-R-beta, platelet-derived growth factor receptor, beta polypeptide
ID gène 5159
Pathways Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Indications d'application Western Blot 1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
Immunohistochemistry 8-25 μg/mL
Immunoprecipitation
Restrictions For Research Use only
Buffer Supplied as a 0.2 μm filtered solution in PBS.
Agent conservateur Without preservative
Stock 4 °C,-20 °C,-80 °C
Stockage commentaire Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C, as supplied. 1 month,2°C to 8°C under sterile conditions after opening. 6 months,-20°C to -70°C under sterile conditions after opening.
Date de péremption 12 months
Images (Fournisseur)
Flow Cytometry (FACS) image for anti-Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) antibody (ABIN4900877) anti-Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) antibody
Produit citée dans: Xu, Chan, Ng, Yeung: "Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle." dans: Experimental cell research, Vol. 350, Issue 1, pp. 184-189, 2017 (PubMed). Méthode utilisée: Immunocytochemistry (ICC) (Échantillon (espèces): Human).

Kiyan, Haller, Dumler: "The tyrosine phosphatase SHP-2 controls urokinase-dependent signaling and functions in human vascular smooth muscle cells." dans: Experimental cell research, Vol. 315, Issue 6, pp. 1029-39, 2009 (PubMed). Méthode utilisée: Western Blotting (WB), Western Blotting (WB), Western Blotting (WB) (Échantillon (espèces): Human).

Ponte, Marais, Gallay, Langonné, Delorme, Hérault, Charbord, Domenech: "The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities." dans: Stem cells (Dayton, Ohio), Vol. 25, Issue 7, pp. 1737-45, 2007 (PubMed). Méthode utilisée: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Échantillon (espèces): Human).

Zhang, Veselits, ONeill, Hou, Reddi, Berlin, Ikeda, Nash, Longnecker, Band, Clark: "Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 7, pp. 4435-43, 2007 (PubMed). Méthode utilisée: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Échantillon (espèces): Mouse (Murine)).

Garderet, Mazurier, Chapel, Ernou, Boutin, Holy, Gorin, Lopez, Doucet, Lataillade: "Mesenchymal stem cell abnormalities in patients with multiple myeloma." dans: Leukemia & lymphoma, Vol. 48, Issue 10, pp. 2032-41, 2007 (PubMed). Méthode utilisée: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Échantillon (espèces): Human).

Kang, Cho, Seo, Yoon, Oh, Choi, Kim: "Efficient induction of oligodendrocytes from human embryonic stem cells." dans: Stem cells (Dayton, Ohio), Vol. 25, Issue 2, pp. 419-24, 2007 (PubMed). Méthode utilisée: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Échantillon (espèces): Human).

Ball, Shuttleworth, Kielty: "Vascular endothelial growth factor can signal through platelet-derived growth factor receptors." dans: The Journal of cell biology, Vol. 177, Issue 3, pp. 489-500, 2007 (PubMed). Méthode utilisée: Immunoprecipitation (IP), Immunoprecipitation (IP), Immunoprecipitation (IP) (Échantillon (espèces): Human).

Li, Maminishkis, Wang, Miller: "PDGF-C and -D induced proliferation/migration of human RPE is abolished by inflammatory cytokines." dans: Investigative ophthalmology & visual science, Vol. 48, Issue 12, pp. 5722-32, 2007 (PubMed). Méthode utilisée: Western Blotting (WB), Western Blotting (WB), Western Blotting (WB) (Échantillon (espèces): Human).

Nagineni, Kutty, Detrick, Hooks: "Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta." dans: Journal of cellular physiology, Vol. 203, Issue 1, pp. 35-43, 2005 (PubMed). Méthode utilisée: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Échantillon (espèces): Human).

Kübler, van Randenborgh, Treiber, Wutzler, Battistel, Lehmer, Wagenpfeil, Hartung, Paul: "In vitro cytotoxic effects of imatinib in combination with anticancer drugs in human prostate cancer cell lines." dans: The Prostate, Vol. 63, Issue 4, pp. 385-94, 2005 (PubMed). Méthode utilisée: Immunocytochemistry (ICC), Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Échantillon (espèces): Human).

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