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BCCIP anticorps

BCCIP Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4903023
  • Antigène Voir toutes BCCIP Anticorps
    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 30
    • 5
    Lapin
    Clonalité
    • 34
    • 1
    Polyclonal
    Conjugué
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BCCIP est non-conjugé
    Application
    • 16
    • 14
    • 13
    • 8
    • 8
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
    Purification
    Affinity purification
    Immunogène
    Recombinant protein of human BCCIP.
    Isotype
    IgG
    Top Product
    Discover our top product BCCIP Anticorps primaire
  • Indications d'application
    WB 1:500-1:2000 , IHC 1:100-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C.
  • Antigène
    BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
    Autre désignation
    BCCIP (BCCIP Produits)
    Synonymes
    anticorps zgc:110272, anticorps mp:zf637-1-000774, anticorps BCCIP, anticorps DKFZp459K2416, anticorps MGC82792, anticorps tok-1, anticorps MGC89311, anticorps TOK-1, anticorps TOK1, anticorps 1110013J05Rik, anticorps BRCA2 and CDKN1A interacting protein, anticorps BRCA2 and CDKN1A interacting protein L homeolog, anticorps BCCIP, anticorps bccip, anticorps bccip.L, anticorps Bccip
    ID gène
    56647
    UniProt
    Q9P287
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