BCR anticorps
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- Antigène Voir toutes BCR Anticorps
- BCR (Breakpoint Cluster Region (BCR))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BCR est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42. Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling.
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human BCR.
- Isotype
- IgG
- Top Product
- Discover our top product BCR Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 , IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C.
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- Antigène
- BCR (Breakpoint Cluster Region (BCR))
- Autre désignation
- BCR (BCR Produits)
- Synonymes
- anticorps si:dkey-83d9.7, anticorps zK83D9.7, anticorps BCR, anticorps ALL, anticorps BCR1, anticorps CML, anticorps D22S11, anticorps D22S662, anticorps PHL, anticorps 5133400C09Rik, anticorps AI561783, anticorps AI853148, anticorps mKIAA3017, anticorps breakpoint cluster region, anticorps BCR, RhoGEF and GTPase activating protein, anticorps bcr, anticorps BCR, anticorps Bcr
- ID gène
- 613
- UniProt
- P11274
- Pathways
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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